Evidence map›Paper›PMID 35646655›Full record

ArticleFrontiers in oncology2022

Network Pharmacology and Transcriptomic Sequencing Analyses Reveal the Molecular Mechanism of

Weijia Zhang, Shuyi Sang, Chang Peng, George Q Li, Ling Ou, Zhong Feng, Yuanjing Zou, Yuemei Yuan, Meicun Yao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Therapeutic Potential of Ziyuglycosides fromDrug design, development and therapy · 2026
    Review
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  4. Heliyon · 2023
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Weijia ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
Shuyi SangSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Chang PengSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
George Q LiInstitute of Natural Products and Metabolomics, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ling OuSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Zhong FengSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Yuanjing ZouSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Yuemei YuanSchool of Ecology, Sun Yat-sen University, Guangzhou, China.
Meicun YaoSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Sun Yat-sen University · CNChengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) is the most common malignant cancer worldwide. Method: Firstly, the active ingredients and potential targets of Results: In total, 14 active ingredients and 273 potential targets against CRC were identified in Conclusion: In conclusion, network pharmacology and transcriptomic sequencing analyses, in combination with

Indexed as

colorectal cancerMAPK pathwaynetwork pharmacologyPI3K–Akt pathwaySanguisorba officinalistranscriptomic sequencing

Identifiers

PMID35646655
PMCPMC9133337
OpenAlexW4280584013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.