Evidence map›Paper›PMID 35646380›Full record

ArticleDigital health

Role of decentralized clinical trials in cancer drug development: Results from a survey of oncologists and patients.

Begoña de Las Heras, Adam Daehnke, Kamal S Saini, Melissa Harris, Kenneth Morrison, Ariel Aguilo, Isagani Chico, Laura Vidal, Robin Marcus

Open access · goldAbstract read
In one paragraph

Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Sample-size determination for decentralized clinical trials.International journal of epidemiology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Narrative review of telemedicine applications in decentralized research.Journal of clinical and translational science · 2024
    Review
  10. Article
  11. Clinical trial reform in the post-COVID era.Therapeutic advances in medical oncology · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Begoña de Las HerasLabcorp Drug Development Inc., Burlington, North Carolina, USA.ORCID https://orcid.org/0000-0003-3091-1684
Adam DaehnkeLabcorp Drug Development Inc., Burlington, North Carolina, USA.
Kamal S SainiLabcorp Drug Development Inc., Burlington, North Carolina, USA.ORCID https://orcid.org/0000-0001-6301-3309
Melissa HarrisLabcorp Drug Development Inc., Burlington, North Carolina, USA.
Kenneth MorrisonLabcorp Drug Development Inc., Burlington, North Carolina, USA.
Ariel AguiloLabcorp Drug Development Inc., Burlington, North Carolina, USA.ORCID https://orcid.org/0000-0001-5002-1748
Isagani ChicoLabcorp Drug Development Inc., Burlington, North Carolina, USA.
Laura VidalLabcorp Drug Development Inc., Burlington, North Carolina, USA.
Robin MarcusLabcorp Drug Development Inc., Burlington, North Carolina, USA.
LabCorp (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a result of the unprecedented challenges imposed by the COVID-19 pandemic on enrollment to cancer clinical trials, there has been an urgency to identify and incorporate new solutions to mitigate these difficulties. The concept of decentralized or hybrid clinical trials has rapidly gained currency, given that it aims to reduce patient burden, increase patient enrollment and retention, and preserve quality of life, while also increasing the efficiency of trial logistics. Therefore, the clinical trial environment is moving toward remote collection and assessment of data, transitioning from the classic site-centric model to one that is more patient-centric.

Indexed as

cancerCOVID-19 pandemicDecentralized clinical trialshybridoncologypatient centricityremote clinical trialsurveytele-oncologyvirtual

Identifiers

PMID35646380
PMCPMC9136463
OpenAlexW4282939617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.