Evidence map›Paper›PMID 35646225›Full record

ArticleJournal of medical devices2022

DynaRing: A Patient-Specific Mitral Annuloplasty Ring With Selective Stiffness Segments.

Samuel Frishman, Ali Kight, Ileana Pirozzi, Sainiteesh Maddineni, Annabel M Imbrie-Moore, Zulekha Karachiwalla, Michael J Paulsen, Alexander D Kaiser, Y Joseph Woo, Mark R Cutkosky

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical devices, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Samuel Frishman *Department of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Ali Kight *Department of Bioengineering, Stanford University, Stanford, CA 94305.
Ileana Pirozzi *Department of Bioengineering, Stanford University, Stanford, CA 94305.
Sainiteesh MaddineniDepartment of Bioengineering, Stanford University, Stanford, CA 94305.
Annabel M Imbrie-MooreDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Zulekha KarachiwallaDepartment of Computer Engineering, University of Maryland, Baltimore, MD 21250.
Michael J PaulsenDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305.
Alexander D KaiserICME and Department of Pediatrics, Stanford University, Stanford, CA 94305.
Y Joseph WooDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305.
Mark R CutkoskyDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305.
Stanford University · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Annuloplasty ring choice and design are critical to the long-term efficacy of mitral valve (MV) repair. DynaRing is a selectively compliant annuloplasty ring composed of varying stiffness elastomer segments, a shape-set nitinol core, and a cross diameter filament. The ring provides sufficient stiffness to stabilize a diseased annulus while allowing physiological annular dynamics. Moreover, adjusting elastomer properties provides a mechanism for effectively tuning key MV metrics to specific patients. We evaluate the ring embedded in porcine valves with an ex-vivo left heart simulator and perform a 150 million cycle fatigue test via a custom oscillatory system. We present a patient-specific design approach for determining ring parameters using a finite element model optimization and patient MRI data. Ex-vivo experiment results demonstrate that motion of DynaRing closely matches literature values for healthy annuli. Findings from the patient-specific optimization establish DynaRing's ability to adjust the anterior-posterior and intercommissural diameters and saddle height by up to 8.8%, 5.6%, 19.8%, respectively, and match a wide range of patient data.

Identifiers

PMID35646225
PMCPMC9125864
OpenAlexW4225113105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.