Evidence map›Paper›PMID 35646160›Full record

ArticleTherapeutic advances in neurological disorders2022

Leaving the day behind: endovascular therapy beyond 24 h in acute stroke of the anterior and posterior circulation.

Jan C Purrucker, Peter A Ringleb, Fatih Seker, Arne Potreck, Simon Nagel, Silvia Schönenberger, Anne Berberich, Ulf Neuberger, Markus Möhlenbruch, Charlotte Weyland

Registry-linked trialAbstract read
In one paragraph

Article in Therapeutic advances in neurological disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06560203 (Safety and Efficacy of Endovascular Treatment for Acute Basilar Artery Occlusion in the Extended Time Window -a Prospective, Multicenter, Randomized Controlled, Open-label Clinical Trial), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06560203 narecruitingnot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy of Endovascular Treatment for Acute Basilar Artery Occlusion in the Extended Time Window -a Prospective, Multicenter, Randomized Controlled, Open-label Clinical Trial

TypeinterventionalSponsorCapital Medical UniversityRan2024 to 2026Enrolled309ConditionsAcute Ischemic Stroke, Basilar Artery OcclusionArmsMechanical thrombectomy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Safety and efficacy of endovascular treatment for acute ischemic stroke of large-vessel occlusion beyond the time window based on imaging evaluation.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  5. Mechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jan C PurruckerDepartment of Neurology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.ORCID https://orcid.org/0000-0003-2978-4972
Peter A RinglebDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Fatih SekerDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Arne PotreckDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Simon NagelDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Silvia SchönenbergerDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Anne BerberichDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Ulf NeubergerDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Markus MöhlenbruchDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Charlotte WeylandDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is little evidence of endovascular therapy (EVT) being performed in acute ischemic stroke beyond 24 h, and that evidence is limited to anterior circulation stroke. Objective: To extend evidence of efficacy and safety of EVT after more than 24 h in both anterior and posterior circulation stroke. Methods: Local, prospectively collected registries were screened for patients with acute ischemic stroke and large-vessel occlusion who had received either EVT > 24 h after last-seen-well but <24 h after symptom recognition (EVT Results: Between January 2014 and August 2021, Conclusion: In selected patients, EVT seems effective and safe beyond 24 h for both anterior and posterior circulation stroke.

Indexed as

endovascular therapyischemic strokethrombectomy

Identifiers

PMID35646160
PMCPMC9136439

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.