Evidence map›Paper›PMID 35645961›Full record

ArticleFrontiers in neurology2022

Risk Assessment of Cnm-Positive

Satoshi Hosoki, Yorito Hattori, Satoshi Saito, Misa Takegami, Shuichi Tonomura, Yumi Yamamoto, Shuhei Ikeda, Naohisa Hosomi, Naoya Oishi, Yoshiaki Morita and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Raman signatures ofFrontiers in microbiology · 2026
    Article
  2. Article
  3. Raman signatures ofFrontiers in microbiology · 2026
    Article
  4. Raman signatures ofFrontiers in microbiology · 2026
    Article
  5. Observational
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Satoshi HosokiDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Yorito HattoriDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Satoshi SaitoDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Misa TakegamiDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Shuichi TonomuraDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Yumi YamamotoDepartment of Molecular Innovation in Lipidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Shuhei IkedaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Naohisa HosomiDepartment of Neurology, Chikamori Hospital, Kochi, Japan.
Naoya OishiMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yoshiaki MoritaDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Yoshihiro MiyamotoDepartment of Medical and Health Information Management, National Cerebral and Cardiovascular Center, Suita, Japan.
Ryota NomuraDepartment of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Suita, Japan.
Kazuhiko NakanoDepartment of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Suita, Japan.
Masafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
National Cerebral and Cardiovascular Center · JPKyoto University · JPOsaka University · JPChikamori Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The role of commensal microbiota in systemic diseases, including brain diseases, has attracted increasing attention. Oral infectious diseases, such as dental caries and periodontitis, are also involved in cerebrovascular diseases and cognitive impairment. Cerebral microbleeds (CMBs) and intracerebral hemorrhage due to small vessel disease (SVD), are presumably associated with a high risk of vascular cognitive impairment and stroke. We previously reported that Methods: Fifteen domestic institutes will be enlisted to enroll 230 patients who have at least one CMB in the deep brain area and develop a stroke within the past year. The prevalence of Cnm-positive Discussion: The 2-year longitudinal prospective cohort study is expected to establish the role of Cnm-positive

Indexed as

cerebral microbleeds (CMBs)Cnmdental cariesintracerebral hemorrhage (ICH)small vessel disease (SVD)Streptococcus mutans (S. mutans)stroke

Identifiers

PMID35645961
PMCPMC9133813
OpenAlexW4280559244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.