ArticleFrontiers in neuroscience2022
Quantification of Intracranial Structures Volume in Fetuses Using 3-D Volumetric MRI: Normal Values at 19 to 37 Weeks' Gestation.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Towards improving outcomes: Protein, body composition, and brain development in preterm infants.Pediatric research · 2026Article
- Super-resolution MRI-derived brainstem and cerebellar volumes in fetuses between 22 weeks and 32 weeks of gestation.Pediatric radiology · 2026Article
- Normative growth trajectories of fetal brain regions validated by satisfactory maturation of neurodevelopmental domains at 2 years of age.Nature communications · 2026Article
- The early alteration of brainstem and cerebellum, and their relationship with cerebral cortex: anQuantitative imaging in medicine and surgery · 2025Article
- The Impacts of Enlarged Subarachnoid Space on Brain Growth and Cortex Maturation in Very Preterm Infants.Diagnostics (Basel, Switzerland) · 2025Article
- Slice-to-Volume Reconstruction of Fetal Brain MR Imaging in Clinical Practice.AJNR. American journal of neuroradiology · 2025Article
- Analysis of automatic fetal intracranial volume (ICV) measurement based on the optimized ultrasound Smart ICV method at 16-34 weeks of gestation.Quantitative imaging in medicine and surgery · 2024Article
- Assessment of fetal corpus callosum biometry by 3D super-resolution reconstructed T2-weighted magnetic resonance imaging.Frontiers in neurology · 2024Article
- Effect of magnet strength on fetal brain biometry - a single-center retrospective MRI-based cohort study.Neuroradiology · 2023Article
- Default mode network functional connectivity strength in utero and the association with fetal subcortical development.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Concordance between US and MRI Two-Dimensional Measurement and Volumetric Segmentation in Fetal Ventriculomegaly.Diagnostics (Basel, Switzerland) · 2023Article
- Systematic review and meta-analysis of MRI-based sex differences in the human fetal brain.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The purpose of this study is to establish a reference of intracranial structure volumes in normal fetuses ranging from 19 to 37 weeks' gestation (mean 27 weeks). Materials and Methods: A retrospective analysis of 188 MRI examinations (1.5 T) of fetuses with a normal brain appearance (19-37 gestational weeks) from January 2018 to December 2021 was included in this study. Three dimensional (3-D) volumetric parameters from slice-to-volume reconstructed (SVR) images, such as total brain volume (TBV), cortical gray matter volume (GMV), subcortical brain tissue volume (SBV), intracranial cavity volume (ICV), lateral ventricles volume (VV), cerebellum volume (CBV), brainstem volume (BM), and extra-cerebrospinal fluid volume (e-CSFV), were quantified by manual segmentation from two experts. The mean, SD, minimum, maximum, median, and 25th and 75th quartiles for intracranial structures volume were calculated per gestational week. A linear regression analysis was used to determine the gestational weekly age-related change adjusted for sex. A Results: The intracranial volume data are shown in graphs and tabular summaries. The male fetuses had significantly larger VV compared with female fetuses ( Conclusion: We have shown that the intracranial structural volume of the fetal brain can be reliably quantified using 3-D volumetric MRI with a high degree of reproducibility and reinforces the existing data with more robust data in the earlier second and third stages of pregnancy.
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