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ArticleInternational journal of clinical pediatric dentistry2022

Clinical Radiographic Evaluation of 3Mixtatin and MTA in Primary Teeth Pulpotomies: A Randomized Controlled.

Rakesh K Chak, Rajeev K Singh, Jhansi Mutyala, Nidesh K Killi

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in International journal of clinical pediatric dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05677945 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized Controlled Trial Comparing the Clinical and Radiographic Success of 3Mixtatin Versus Modified 3Mix in Lesion Sterilization and Tissue Repair (LSTR) for The Treatment of Necrotic Primary Molars

TypeinterventionalSponsorCairo UniversityRan2023 to 2024Enrolled24ConditionsNecrotic Primary MolarsArms3Mixtatin paste: Simvastatin mixed with modified triple antibiotic, 3Mix: Modified triple antibiotic mix in propylene glycol
NCT06478940 phase1unknown statusnot on this mapstarted 2024, after this paper: background citation

Clinical and Radiographic Evaluation of 3Mixtatin Versus MTA Used as Pulpotomy Agents in Vital Primary Molars: A Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled50ConditionsPulp Disease, Dental, Deciduous TeethArms3 mixtatin pulpotomy, MTA pulpotomy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Effect of Simvastatin on Success of Pulpotomy in Carious Permanent Molars With Symptomatic Irreversible Pulpitis: A Randomised Controlled Trial.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rakesh K ChakDepartment of Paediatric and Preventive Dentistry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Rajeev K SinghDepartment of Paediatric and Preventive Dentistry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Jhansi MutyalaDepartment of Paediatric and Preventive Dentistry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Nidesh K KilliDepartment of Paediatric and Preventive Dentistry, GITAM Dental College and Hospital, Vishakapatnam, Andhra Pradesh, India.
King George's Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The present study evaluates the efficiency of 3Mixtatin (a combination of Simvastatin and 3Mix antibiotics) in comparison with Mineral Trioxide Aggregate in primary molars pulpotomy. Materials and methods: A total of 64 deciduous molar teeth with caries requiring pulpotomy procedure were selected and randomly divided into two treatment groups, Group I- MTA ( Result: Both groups showed equal success rates, without any significant difference between the MTA and 3mixtatin groups clinically (success rate of 93.8%)and radiographically higher success rate was seen with 3Mixtatin (78% success rate). Conclusion: 3mixtatin showed similar clinical and better radiographical success rate to MTA. Therefore, 3mixtatin may be a potential alternate pulpotomy medicament in primary teeth. Key messages: In the present study based on the radiographic findings, 78% success rate was seen in the teeth treated with 3Mixtatin, which was higher than the radiographic success rate of MTA (75%). Therefore, it is reasonable to assume the use of 3Mix with Simvastatin to treat pulpotomized primary molars by 3Mixtatin. How to cite this article: Chak RK, Singh RK, Mutyala J,

Indexed as

3MixtatinBiodentinPrimary molarsPulpotomy

Identifiers

PMID35645497
PMCPMC9108818
OpenAlexW4214819489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.