Evidence map›Paper›PMID 35645386›Full record

Observational studyTomography (Ann Arbor, Mich.)2022

Diagnostic Accuracy of Chest Digital Tomosynthesis in Patients Recovering after COVID-19 Pneumonia.

Elisa Baratella, Barbara Ruaro, Cristina Marrocchio, Gabriele Poillucci, Caterina Pigato, Alessandro Marco Bozzato, Francesco Salton, Paola Confalonieri, Filippo Crimi, Barbara Wade and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Elisa BaratellaDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-1061-9507
Barbara RuaroDepartment of Pulmonology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-8990-859X
Cristina MarrocchioDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-2757-7400
Gabriele PoillucciDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.
Caterina PigatoDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.
Alessandro Marco BozzatoDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-7344-3668
Francesco SaltonDepartment of Pulmonology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-0864-9766
Paola ConfalonieriDepartment of Pulmonology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-7284-5016
Filippo CrimiDepartment of Radiology, University of Padua, Via Nicolò Giustiniani, 2, 35128 Padua, Italy.ORCID 0000-0001-6822-1430
Barbara WadeAOU City of Health and Science of Turin, Department of Science of Public Health and Pediatrics, University of Torino, 10124 Torino, Italy.
Emilio QuaiaDepartment of Radiology, University of Padua, Via Nicolò Giustiniani, 2, 35128 Padua, Italy.ORCID 0000-0003-2020-9365
Maria Assunta CovaDepartment of Radiology, Cattinara Hospital, University of Trieste, 34127 Trieste, Italy.
University of Trieste · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the diagnostic accuracy of traditional chest X-ray (CXR) and digital tomosynthesis (DTS) compared to computed tomography (CT) in detecting pulmonary interstitial changes in patients having recovered from severe COVID-19. MATERIALS AND

methodsThis was a retrospective observational study, and received local ethics committee approval. Patients suspected of having COVID-19 pneumonia upon emergency department admission between 1 March and 31 August 2020, and who underwent CXR followed by DTS and CT, were considered. Inclusion criteria were as follows: (1) patients with previous SARS-CoV-2 infection proven by a positive RT-PCR on nasopharyngeal swabs performed upon admission to the hospital, and with complete clinical recovery; (2) a diagnosis of SARS-CoV-2-related ARDS, according to the Berlin criteria, during hospitalization; (3) no recent history of other lung disease; and (4) complete imaging follow-up by CXR, DTS, and CT for at least 6 months and up to one year. Analysis of DTS images was carried out independently by two radiologists with 16 and 10 years of experience in chest imaging, respectively. The following findings were evaluated: (1) ground-glass opacities (GGOs); (2) air-space consolidations with or without air bronchogram; (3) reticulations; and (4) linear consolidation. Indicators of diagnostic performance of RX and digital tomosynthesis were calculated using CT as a reference. All data were analyzed using R statistical software (version 4.0.2, 2020).

resultsOut of 44 patients initially included, 25 patients (17 M/8 F), with a mean age of 64 years (standard deviation (SD): 12), met the criteria and were included. The overall average numbers of findings confirmed by CT were GGOs in 11 patients, lung consolidations in 8 patients, 7 lung interstitial reticulations, and linear consolidation in 20 patients. DTS showed a significantly higher diagnostic accuracy compared to CXR in recognizing interstitial lung abnormalities-especially GGOs (

conclusionsAccording to our results, DTS possesses a high diagnostic accuracy, compared with CXR, in revealing lung fibrotic changes in patients who have recovered from COVID-19 pneumonia.

Indexed as

COVID-19Pulmonary FibrosisHumansMiddle AgedRadiographic Image EnhancementRadiography, ThoracicSARS-CoV-2ARDSchest digital tomosynthesisCOVID-19follow-up

Identifiers

PMID35645386
PMCPMC9149814
OpenAlexW4224692999

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.