Evidence map›Paper›PMID 35645261›Full record

ArticleJournal of functional biomaterials2022

Nanocomposite Hydrogel Produced from PEGDA and Laponite for Bone Regeneration.

Leila S S M Magalhães, Danielle B Andrade, Roosevelt D S Bezerra, Alan I S Morais, Francilio C Oliveira, Márcia S Rizzo, Edson C Silva-Filho, Anderson O Lobo

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. LaponitePharmaceutics · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. LaponiteMolecules (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leila S S M MagalhãesLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.
Danielle B AndradeLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.
Roosevelt D S BezerraFederal Institute of Education, Science and Technology of Piauí, Teresina-Central Campus, IFPI, Teresina 64000-040, Brazil.
Alan I S MoraisLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0002-6974-6455
Francilio C OliveiraCentro Universitário UNINOVAFAPI, Teresina 64073-505, Brazil.
Márcia S RizzoLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0003-4276-3113
Edson C Silva-FilhoLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0003-0988-2970
Anderson O LoboLIMAV-Interdisciplinary Advanced Materials Laboratory, PPGCM-Materials Science and Engineering Graduate Program, UFPI-Federal University of Piaui, Teresina 64049-550, Brazil.ORCID 0000-0002-2544-0438

Funding

National Council for Scientific and Technological Development 310883/2020-2National Council for Scientific and Technological Development 404683/2018
6 · The paper itself

Abstract

Herein, a nanocomposite hydrogel was produced using laponite and polyethylene-glycol diacrylate (PEGDA), with or without Irgacure (IG), for application in bone tissue regeneration. The nanocomposites were characterized by X-ray diffraction (XRD), Fourier-Transform infrared spectroscopy (FTIR), and thermal analysis (TG/DTG). The XRD results showed that the crystallographic structure of laponite was preserved in the nanocomposite hydrogels after the incorporation of PEGDA and IG. The FTIR results indicated that PEGDA polymer chains were entangled on laponite in hydrogels. The TG/DTG found that the presence of laponite (Lap) improved the thermal stability of nanocomposite hydrogel. The toxicity tests by

Indexed as

bone regenerationlaponitenanocomposite hydrogelPEGDA

Identifiers

PMID35645261
PMCPMC9149996

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.