Evidence map›Paper›PMID 35644753›Full record

Trial reportObesity research & clinical practice

Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT.

Emily A Kringle, Nan Lv, Corina R Ronneberg, Nancy Wittels, Lisa G Rosas, Lesley E Steinman, Joshua M Smyth, Ben S Gerber, Lan Xiao, Elizabeth M Venditti and 3 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Emily A KringleDepartment of Medicine, University of Illinois at Chicago, United States.
Nan LvInstitute for Health Research and Policy, University of Illinois at Chicago, United States.
Corina R RonnebergDepartment of Medicine, University of Illinois at Chicago, United States.
Nancy WittelsDepartment of Medicine, University of Illinois at Chicago, United States.
Lisa G RosasDepartment of Epidemiology and Population Health, Stanford University, United States.
Lesley E SteinmanHealth Promotion Research Center, Department of Health Services, University of Washington, United States.
Joshua M SmythDepartment of Biobehavioral Health, Pennsylvania State University, United States.
Ben S GerberDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, United States.
Lan XiaoDepartment of Epidemiology and Population Health, Stanford University, United States.
Elizabeth M VendittiDepartment of Psychiatry, University of Pittsburgh, United States.
Olusola A AjiloreDepartment of Psychiatry, University of Illinois at Chicago, United States.
Leanne M WilliamsDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, United States.
Jun MaDepartment of Medicine, University of Illinois at Chicago, United States. Electronic address: maj2015@uic.edu.
University of Illinois Chicago · USStanford University · USPennsylvania State University · USStanford Medicine · USUniversity of Massachusetts Chan Medical School · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

Engaging self-regulation targets to understand the mechanisms of behavior change and improve mood and weight outcomesUH3HL132368 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MA, JUN, WILLIAMS, LEANNE · 2018 to 2019
$2.6M
Engaging self-regulation targets to understand the mechanisms of behavior change and improve mood and weight outcomesUH2HL132368 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MA, JUN, WILLIAMS, LEANNE · 2015 to 2017
$2.6M
Precision Lifestyle Medicine and Translation Research (PREMIER)T32HL134634 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RACHEL CASKEY, Jun Ma · 2018 to 2026
$2.4M
teleABLE: Adapting a Behavioral Activation-Based Intervention to Reduce Post-Stroke Sedentary Behavior Using TelehealthK23HL159240 · NHLBI · UNIVERSITY OF MINNESOTA · PI KRINGLE, EMILY · 2021 to 2025
$949k
NHLBI NIH HHS K23 HL159240NHLBI NIH HHS T32 HL134634NHLBI NIH HHS UH2 HL132368NHLBI NIH HHS UH3 HL132368
6 · The paper itself

Abstract

objectiveTo examine the association between COVID-19 impact and clinical outcomes of an integrated collaborative care intervention for adults with obesity and comorbid depression.

methodsLatent class analysis identified clusters of self-reported COVID-19 impact. Cluster characteristics were examined using Fishers' least significant difference method and canonical discriminant analysis. Intervention vs. usual care effects on primary (body mass index [BMI], depressive symptoms) and secondary (anxiety symptoms and other psychosocial) outcomes stratified by cluster were examined using linear mixed models.

resultsThree clusters were identified: mental health and sleep impact (cluster 1, n = 37), economic impact (cluster 2, n = 18), and less overall impact (cluster 3, n = 20). Clusters differed in age, income, diet, and baseline coping skills. The intervention led to improvements across several health outcomes compared with usual care, with medium to large effects on functional impairments (standardized mean difference, -0.7 [95% CI: -1.3, -0.1]) in cluster 1, depressive symptoms (-1.1 [95% CI: -2.0, -0.1]) and obesity-related problems (-1.6 [95% CI: -2.8, -0.4]) in cluster 2, and anxiety (-1.1 [95% CI: -1.9, -0.3]) in cluster 3.

conclusionsPeople with obesity and comorbid depression may have varied intervention responses based on COVID-19 impact. Interventions tailored to specific COVID-19 impact clusters may restore post-pandemic health.

Indexed as

COVID-19DepressionAdultAnxietyHumansObesityQuality of LifeBehavioral medicineCOVID-19DepressionInterventionLifestyleObesity

Identifiers

PMID35644753
PMCPMC9119961
OpenAlexW4281898256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.