Evidence map›Paper›PMID 35644403›Full record

ArticleThe Science of the total environment2022

Geomagnetic disturbances reduce heart rate variability in the Normative Aging Study.

Carolina L Zilli Vieira, Kelly Chen, Eric Garshick, Man Liu, Pantel Vokonas, Petter Ljungman, Joel Schwartz, Petros Koutrakis

Open access · greenAbstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Carolina L Zilli VieiraDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address: cazilli@hsph.harvard.edu.
Kelly ChenDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Eric GarshickPulmonary, Allergy, Sleep and Critical Care Medicine Section, Veterans Affairs Boston Healthcare System, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Man LiuDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Pantel VokonasVA Normative Aging Study, Veterans Affairs Boston Healthcare System and the Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Petter LjungmanInstitute of Environmental Medicine, Karolinska Institute, Sweden; Department of Cardiology, Danderyd University Hospital, Stockholm, Sweden.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Harvard University · USBoston University · USDanderyds sjukhus · SE

Funding

Retrospective assessment of radon progeny and pollution effects in COPDR21ES029637 · NIEHS · HARVARD MEDICAL SCHOOL · PI GARSHICK, ERIC · 2019 to 2020
$453k
EPA R835872NIEHS NIH HHS R21 ES029637
6 · The paper itself

Abstract

backgroundSolar and geomagnetic activity (GA) have been linked to increased cardiovascular (CVD) events. We hypothesize that heart rate variability (HRV) may be the biological mechanism between increased CVD risk and intense geomagnetic disturbances (GMD).

methodsTo evaluate the impact of GA and intense GMD on HRV in 809 elderly men [age mean 74.5 (SD = 6.8)] enrolled in the Normative Aging Study (Greater Boston Area), we performed repeated-measures using mixed-effects regression models. We evaluated two HRV outcomes: the square root of the mean squared differences of successive normal-to-normal intervals (r-MSSD) and the standard deviation of normal-to-normal heartbeat intervals (SDNN) in milliseconds (ms). We also compared the associations between K

resultsWe found a near immediate effect of continuous and higher K

conclusionsThis is the first study to demonstrate the potential adverse effects of geomagnetic activity on reduced heart rate variability in a large epidemiologic cohort over an extended period, which may have important clinical implications among different populations.

Indexed as

Air PollutantsCoronary DiseaseAgedAgingElectrocardiographyHeart RateHumansMaleAir PollutantsCardiovascular riskCircadian rhythm dysregulationReduced heart rateSolar and geomagnetic activity

Identifiers

PMID35644403
PMCPMC9233046
OpenAlexW4281567612

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.