Evidence map›Paper›PMID 35644302›Full record

ArticlePeptides2022

A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity.

Gloria Gallo, Uilla Barcick, Camila Coelho, Murilo Salardani, Maurício F Camacho, Daniela Cajado-Carvalho, Flávio V Loures, Solange M T Serrano, Leon Hardy, André Zelanis and 1 more

Abstract read
In one paragraph

Article in Peptides, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Discovery of a novel and potent KRASJournal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gloria GalloDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Uilla BarcickDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Camila CoelhoDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Murilo SalardaniDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Maurício F CamachoDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Daniela Cajado-CarvalhoLaboratory of Applied Toxinology, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Butantan Institute, São Paulo, Brazil.
Flávio V LouresDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Solange M T SerranoLaboratory of Applied Toxinology, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Butantan Institute, São Paulo, Brazil.
Leon HardyDepartment of Physics, University of South Florida, Tampa, United States.
André ZelanisDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Martin WürteleDepartment of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil. Electronic address: martin.wurtele@unifesp.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main protease M

Indexed as

COVID-19SARS-CoV-2AnimalsCoronavirus 3C ProteasesMiceMolecular Docking SimulationMolecular Dynamics SimulationPeptidesProtease InhibitorsProteomics3C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesPeptidesProtease InhibitorsCOVID-19Free energy calculationsMain proteaseMM/PBSAProteomicsTAILS

Identifiers

PMID35644302
PMCPMC9134770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.