Evidence map›Paper›PMID 35643873›Full record

Trial reportEuropean journal of nutrition2022

Vitamin D supplementation and increased dairy protein intake do not affect muscle strength or physical function in healthy 6-8-year-old children: the D-pro randomized trial.

Line Thams, Lars G Hvid, Nanna G Stounbjerg, Jan C Brønd, Christian Mølgaard, Camilla T Damsgaard, Mette Hansen

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Line ThamsSection of Sports Science, Department of Public Health, Aarhus University, Aarhus, Denmark. thams@ph.au.dk.ORCID http://orcid.org/0000-0003-4395-1394
Lars G HvidSection of Sports Science, Department of Public Health, Aarhus University, Aarhus, Denmark.
Nanna G StounbjergDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Jan C BrøndCenter for Research in Childhood Health, Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Christian MølgaardDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Camilla T DamsgaardDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Mette HansenSection of Sports Science, Department of Public Health, Aarhus University, Aarhus, Denmark.
Aarhus University · DKUniversity of Copenhagen · DKUniversity of Southern Denmark · DK

Funding

Arla Food for Health 2018Augustinus Fonden 19-1300Familien Hede Nielsens Fond 32880
6 · The paper itself

Abstract

purposeTo investigate separate and combined effects of vitamin D supplementation during the extended winter and increased dairy protein intake on muscle strength and physical function in children, and furthermore to explore potential sex differences.

methodsIn a 2 × 2-factorial, randomized winter trial, 183 healthy, 6-8-year-old children received blinded tablets with 20 µg/day vitamin D

resultsBaseline (mean ± SD) serum 25-hydroxyvitamin D was 80.8 ± 17.2 nmol/L, which increased to 88.7 ± 17.6 nmol/L with vitamin D supplementation and decreased to 48.4 ± 19.2 nmol/L with placebo. Baseline protein intake was 15.5 ± 2.4 E%, which increased to 18.4 ± 3.4 E% with HP and was unchanged with NP. We found no separate or combined effects of vitamin D supplementation and/or increased dairy protein intake on muscle strength or physical function (all P > 0.20). There was an interaction on the sit-to-stand test (P

conclusionOverall, vitamin D and dairy protein supplementation during the extended winter did not affect muscle strength or physical function in healthy children. Potential sex differences of vitamin D supplementation should be investigated further. REGISTERED AT CLINICALTRIALS.GOV: NCT0395673.

Indexed as

CholecalciferolDietary SupplementsMilk ProteinsMuscle StrengthVitamin D DeficiencyChildDouble-Blind MethodFemaleHand StrengthHumansMaleSex FactorsCholecalciferolMilk ProteinsDietDietary supplementsMilk proteinMuscle functionPediatricPhysical performance

Identifiers

PMID35643873
PMCPMC9146815
OpenAlexW4281756037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.