Evidence map›Paper›PMID 35643817›Full record

ArticleArchives of orthopaedic and trauma surgery2023

How does systemic lupus erythematosus impact the peri-operative complication rates in primary hip arthroplasty? A national inpatient sample-based study.

Vibhu Krishnan Viswanathan, Vishaal Sakthivelnathan, Anil Menedal, Prabhudev Prasad Purudappa, Varatharaj Mounasamy, Senthil Sambandam

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In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Impact of systemic lupus erythematosus on adverse outcomes and readmission after total shoulder arthroplasty: a Nationwide Readmission Database analysis 2016-2020.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Vibhu Krishnan ViswanathanDepartment of MSK Oncology, University of Calgary, Calgary, AB, Canada. drvibu007@gmail.com.ORCID http://orcid.org/0000-0002-3804-1698
Vishaal SakthivelnathanSchool of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Anil MenedalSalem VA Medical Center, Salem, VA, USA.
Prabhudev Prasad PurudappaBoston University, Boston VAMC, Boston, MA, USA.
Varatharaj MounasamyDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Senthil SambandamUniversity of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Dallas VA Medical Center · USBoston University · USSalem VA Medical Center · USThe University of Texas Medical Branch at Galveston · USUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWith prolonged life expectancy, the number of patients with systemic lupus erythematosus (SLE) undergoing total hip arthroplasty (THA) has substantially increased over the past years. The post-operative outcome and complications in SLE are less clearly understood than other inflammatory diseases, due to limited availability of evidence within the literature.

methodsUsing the National Inpatient Sample (NIS) database, patients who underwent THA between 2016 and 2019 were identified (ICD-10 CMP code). Patients were then classified into one of the two groups, namely those with SLE (ICD-10-CM; code710.0) or those without SLE (NSLE). Data regarding demographic details, co-morbidities, details regarding hospital stay, expenditure incurred, and complications encountered were analyzed, and compared between the groups.

resultsOverall, among 367,894 patients undergoing THA, 1684 (0.5%) had SLE. Mean age of SLE (57.3 ± 14.5 years) patients undergoing THA was significantly lower than NSLE (65.9 ± 11.4 years) population (p = 0.001). There was a greater proportion of female patients in SLE group [89.6% (SLE) vs 55.8% (NSLE); p = 0.001]. SLE patients had a greater incidence of emergent hospital admissions (p = 0.04), longer hospital stay (p = 0.001), and higher hospital-related expenditure (p = 0.001). Among the peri-operative complications, SLE patients had significantly greater risk of developing post-operative anemia (p = 0.001), need for blood transfusion (p = 0.001), peri-prosthetic mechanical complications (p = 0.04), and prosthetic dislocations (p = 0.001). There was also a greater incidence of peri-prosthetic infections in the SLE group (p = 0.001).

conclusionThe presence of SLE significantly lengthens hospital stay and augments healthcare-related costs in patients undergoing THA. The three main complications which may significantly affect the post-operative course of these patients include higher rates of post-operative anemia, peri-prosthetic infections, and early prosthetic dislocations.

Indexed as

Arthroplasty, Replacement, HipLupus Erythematosus, SystemicAdultAgedFemaleHumansInpatientsLength of StayMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsComplicationsPeriprosthetic joint infectionSystemic lupus erythematosusTotal knee arthroplasty

Identifiers

PMID35643817
OpenAlexW4281866369

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.