Evidence map›Paper›PMID 35643053›Full record

ReviewJournal of infection and public health2022

Venous and arterial thrombosis in COVID-19: An updated narrative review.

Zainab Al Duhailib, Simon Oczkowski, Kamil Polok, Jakub Fronczek, Wojciech Szczeklik, Joshua Piticaru, Manoj J Mammen, Fayez Alshamsi, John Eikelboom, Emilie Belley-Cote and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Antiplatelet agents for the treatment of adults with COVID-19.The Cochrane database of systematic reviews · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Zainab Al DuhailibDepartment of Critical Care Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. Electronic address: zalduhailib65@kfshrc.edu.sa.
Simon OczkowskiDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Kamil PolokCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Jakub FronczekCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Wojciech SzczeklikCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Joshua PiticaruDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Manoj J MammenDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, University of Rochester, USA.
Fayez AlshamsiDepartment of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
John EikelboomPopulation Health Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Emilie Belley-CotePopulation Health Research Institute, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Waleed AlhazzaniDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Department of Critical Care, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Jagiellonian University · PLMcMaster University · CAAlfaisal University · SAImpact · CAPopulation Health Research Institute · CAUnited Arab Emirates University · AEUniversity of Rochester · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospitalized patients with coronavirus disease 2019 (COVID-19), particularly those admitted to the intensive care unit (ICU) are at high risk of morbidity and mortality. Several observational studies have described hemostatic derangements and thrombotic complications in patients with COVID-19. The aim of this review article is to summarize the current evidence on pathologic findings, pathophysiology, coagulation and hemostatic abnormalities, D-dimer's role in prognostication epidemiology and risk factors of thrombotic complications, and the role of prophylactic and therapeutic anticoagulation in patients with COVID-19. While existing evidence is limited in quality, COVID-19 appears to increase micro-and macro-vascular thrombosis rates in hospitalized and critically ill patients, which may contribute to the burden of disease. D-dimer can be used for risk stratification of hospitalized patients, but its role to guide anticoagulation therapy remains unclear. Evidence of higher quality is needed to address the role of therapeutic anticoagulation or high-intensity venous thromboembolism prophylaxis in COVID-19 patients. TAKE-HOME POINTS.

Indexed as

COVID-19HemostaticsThrombosisAnticoagulantsHumansSARS-CoV-2AnticoagulantsHemostaticsAnticoagulationCOVID-19Critically illD-dimer levelThrombosisVenous thromboembolism prophylaxis

Identifiers

PMID35643053
PMCPMC9106398
OpenAlexW4280533255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.