Evidence map›Paper›PMID 35642882›Full record

ArticleJournal of clinical laboratory analysis2022

Unusual morphologic features of low-grade endometrial stromal sarcoma: A case report.

Ling Li Meng, Xiu Peng Jia, Li Xia Lu, Hui Zhi Zhang, Xiao Han Shen, Zheng Hua Piao, Rong Ge, Wen Ying Yu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ling Li MengDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0003-4795-7021
Xiu Peng JiaDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
Li Xia LuDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
Hui Zhi ZhangDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
Xiao Han ShenDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0003-1262-9853
Zheng Hua PiaoDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
Rong GeDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
Wen Ying YuDepartment of Pathology, Ningbo Diagnostic Pathology Center, Huan Cheng Bei Lu, Ningbo, Zhejiang, China.
University of Nottingham Ningbo China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometrial stromal tumours are uncommon tumours of the uterus. They mainly occur in perimenopausal women. Tumours with typical clinicopathological features do not usually pose diagnostic problems. However, rare clinicopathological features can occur, and clinicians without significant experience may have difficulty diagnosing these tumours and managing these patients.

methodsHerein, we report a case of endometrial stromal sarcoma that occurred in a 25-year-old woman. The pathological features, immunophenotype, treatment and prognosis were discussed.

resultsThe tumour revealed morphological heterogeneity, and there were similar proliferative-type endometrial stromal cells, an extensive amount of mature adipose tissue, and prominent rhabdomyoblastic and smooth muscle cells. Histopathological and immunohistochemical studies confirmed low-grade endometrial stromal sarcoma with smooth muscle, adipocytic and rhabdomyoblastic differentiation (approximately 60% were differentiated tissues). The final treatment of the tumour was total abdominal hysterectomy with bilateral salpingo-oophorectomy. There was no evidence of recurrence for 109 months postoperatively.

conclusionsWe found that low-grade endometrial stromal tumours with extensive adipocytic and prominent rhabdomyoblastic differentiation are misdiagnosed because they are infrequent. They must be differentiated from rhabdomyosarcoma with accurate identification of adipocytes, and long-term follow-up is needed.

Indexed as

Endometrial NeoplasmsEndometrial Stromal TumorsSarcoma, Endometrial StromalAdultFemaleHumansPrognosisadipocytic differentiationendometrial stromal tumoursrhabdomyoblastic differentiationsmooth muscle differentiationunusual morphologic features

Identifiers

PMID35642882
PMCPMC9280001
OpenAlexW4281655590

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.