Evidence map›Paper›PMID 35642425›Full record

ArticleJournal of the Royal Society, Interface2022

Sensitivity analysis on a network model of glymphatic flow.

Kimberly A S Boster, Jeffrey Tithof, Douglas D Cook, John H Thomas, Douglas H Kelley

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. MR-AIV revealsbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. InferringInterface focus · 2024
    Article
  6. Article
  7. Article
  8. A brain-wide solute transport model of the glymphatic system.Journal of the Royal Society, Interface · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Cerebrospinal Fluid Flow.Annual review of fluid mechanics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kimberly A S BosterDepartment of Mechanical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0001-5178-128X
Jeffrey TithofDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Douglas D CookDepartment of Mechanical Engineering, Brigham Young University, Provo, UT 84602, USA.
John H ThomasDepartment of Mechanical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0002-7127-8654
Douglas H KelleyDepartment of Mechanical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0001-9658-2954
University of Rochester · USBrigham Young University · USUniversity of Minnesota · US

Funding

Age and AD related bottlenecks in glymphatic-lymphatic waste transportRF1AG057575 · NIA · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2017 to 2017
$3.2M
NIA NIH HHS RF1 AG057575
6 · The paper itself

Abstract

Intracranial cerebrospinal and interstitial fluid (ISF) flow and solute transport have important clinical implications, but limited

Indexed as

BrainExtracellular FluidAnimalsHumansMicecerebrospinal fluidcomputational modellingglymphatic systemperivascular spacesreduced-order modellingsensitivity analysis

Identifiers

PMID35642425
PMCPMC9156905
OpenAlexW4281623455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.