Evidence map›Paper›PMID 35642195›Full record

ArticlePeerJ2022

The impact of different feeds on DNA methylation, glycolysis/gluconeogenesis signaling pathway, and gene expression of sheep muscle.

Feng Song, Zaccheaus Pazamilala Akonyani, Ying Li, Deqiqige Su, Lantuya Wu, Yue Pang, Sile Hu, Dubala Wu, Chun Li, Ding Yang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Feng Song *College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Zaccheaus Pazamilala Akonyani *College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Ying LiCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Deqiqige SuCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Lantuya WuCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Yue PangCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Sile HuCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Dubala WuCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Chun LiCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Ding YangInner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, Inner Mongolia, China.
Jianghong WuCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, Inner Mongolia, China.
Minzu University of China · CNInner Mongolia Academy of Agricultural & Animal Husbandry Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is an important epigenetic regulatory form that regulates gene expression and tissue development. This study compared the effects of high fiber, low protein (HFLP) and low fiber, high protein (LFHP) diets on the DNA methylation profile of twin lambs' muscles, their effect on glycolysis/gluconeogenesis and related pathways by transcriptome and deep whole-genome bisulfite sequencing (WGBS). Results identified 1,945 differentially methylated regions (DMRs) and 1,471 differentially methylated genes (DMGs). Also, 487 differentially expressed transcripts belonging to 368 differentially expressed genes (DEGs) were discovered between the twin lambs under different diets. Eleven overlapped genes were detected between the DEGs and the DMGs.

Indexed as

DNA MethylationGluconeogenesisAnimalsGlycolysisMusclesSheepSignal TransductionTranscriptomecAMP pathwayDNA methylationGlucose metabolismGlycolysis/GluconeogenesisWhole-genome bisulfite sequencing

Identifiers

PMID35642195
PMCPMC9148555
OpenAlexW4281560072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.