Evidence map›Paper›PMID 35642154›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2022

[Effects of Extracellular Vesicles on the Drug Resistance of Lung Adenocarcinoma Cells by Modulating the ATP Binding Cassette Transporter G2].

Lei Wang, Yuan Mi, Xin-Fei Zhang, Xing Li, Cai-Yi He, Chao Li, Liang Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lei WangDepartment of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Yuan MiDepartment of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Xin-Fei ZhangTumor Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Xing LiTumor Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Cai-Yi HeTumor Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Chao LiDepartment of Anesthesiology, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Liang LiuTumor Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the regulatory role of extracellular vesicles (EVs) carrying ATP binding cassette transporter G2 (ABCG2) on the drug resistance of lung adenocarcinoma cells and the relevant molecular mechanisms. Methods: A549 cells, human lung adenocarcinoma cells, were used to form cisplatin (or cis-Diaminedichloroplatinum, CDDP)-resistant lung adenocarcinoma cells, i.e., A549/CDDP cells. EVs from A549 and A549/CDDP cells were extracted by gradient centrifugation method and were hence named EVs Results: Using the parental A549 cells as reference, the 24-h CDDP-resistance indexes of 549/CDDP, A549/ Conclusion: EVs carrying ABCG2 gene can regulate the drug resistance of lung adenocarcinoma cells.

Indexed as

AdenocarcinomaAdenocarcinoma of LungExtracellular VesiclesLung NeoplasmsAnimalsCell Line, TumorCisplatinDrug Resistance, NeoplasmMiceMice, NudeCisplatinATP binding cassette transporter G2Drug resistanceExtracellular vesicleNon-small cell lung cancerNude mice

Identifiers

PMID35642154
PMCPMC10409431
OpenAlexW4282930147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.