Evidence map›Paper›PMID 35642115›Full record

ArticleReviews on recent clinical trials2022

Satisfaction with Social Roles and Physical Function in Immune-mediated Inflammatory Diseases: A Cross-Sectional Study.

Rocco Spagnuolo, Francesco Salvatore Iaquinta, Daniele Mauro, Ilenia Pantano, Stefano Dastoli, Saverio Naty, Cristina Cosco, Rosellina Margherita Mancina, Daniela Iacono, Emanuela Gaggiano and 5 more

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In one paragraph

Article in Reviews on recent clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Rocco SpagnuoloDepartment of Clinical and Experimental Medicine, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.ORCID 0000-0002-0871-4644
Francesco Salvatore IaquintaDepartment of Health Sciences, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.ORCID 0000-0001-9740-1203
Daniele MauroDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.ORCID 0000-0002-9022-8863
Ilenia PantanoDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.
Stefano DastoliDepartment of Health Sciences, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.ORCID 0000-0002-4179-8261
Saverio NatyDepartment of Health Sciences, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.
Cristina CoscoDepartment of Clinical and Experimental Medicine, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.
Rosellina Margherita MancinaDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-1126-3071
Daniela IaconoDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.
Emanuela GaggianoDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.
Annarita RuggieroDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.
Steven Paul NisticòDepartment of Health Sciences, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.
Francesco CicciaDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.ORCID 0000-0002-9352-1264
Rosa Daniela GrembialeDipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Italy.ORCID 0000-0002-0338-6784
Doldo PatriziaDepartment of Clinical and Experimental Medicine, Magna Graecia University of Catanzaro, Calabria, Catanzaro, Italy.
Magna Graecia University · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough mood disorders have been well characterized by immunemediated inflammatory diseases, physical function and satisfaction with social roles have not yet been defined as independent domains.

objectiveThe study aims to assess satisfaction with social roles and physical function alterations in a population with immune-mediated inflammatory diseases and identify associated characteristics.

methodsPhysical function and social role satisfaction were evaluated through the Patientreported Outcomes Measurement System. Besides comparison between groups, univariate and multivariable logistic regression analyses were performed to identify independent predictors.

resultsTwo hundred sixty-five patients with immune-mediated inflammatory diseases and 206 controls were recruited. Compared to controls, patients with inflammatory bowel diseases had impaired physical function (p<0.001), while patients with inflammatory arthritis reported impairment in both domains (p<0.001, each). In the univariate logistic regression, gender, high school educational level, physical activity, and occupation were positively associated with physical function and social role satisfaction (p<0.001; p=0.001; p<0.001; p=0.001 and p<0.001; p=0.012; p=0.008; p=0.004, respectively). Active disease and steroids were inversely associated with physical function and social roles satisfaction (p=0.033; p=0.022 and p=0.002; p=0.038, respectively). Further associations were found between age and physical function (p=0.002) and biological treatment and ESR with social roles satisfaction (p<0.001; p=0.043; respectively). In the multivariable regression, gender was found to be associated with physical function (p<0.001) and social roles satisfaction (p=0.003). Negatively associated factors were biological treatment for satisfaction with social roles (p<0.001) and steroids for physical function (p=0.021), and social roles satisfaction (p=0.018).

conclusionImmune-mediated inflammatory diseases determine alterations in physical function and social life satisfaction. Gender and treatment are independently associated factors. Patientreported outcomes should be considered in clinical management to define patients' real needs.

Indexed as

InflammationInflammatory Bowel DiseasesPersonal SatisfactionAdultAgedCross-Sectional StudiesExerciseFemaleHumansMaleMiddle AgedImmune-mediated inflammatory diseasesinflammatory arthritisinflammatory bowel diseasephysical functionPROMISpsoriasissocial satisfaction.

Identifiers

PMID35642115
OpenAlexW4281711344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.