Evidence map›Paper›PMID 35641505›Full record

ArticleScientific reports2022

Epidural anesthesia needle guidance by forward-view endoscopic optical coherence tomography and deep learning.

Chen Wang, Paul Calle, Justin C Reynolds, Sam Ton, Feng Yan, Anthony M Donaldson, Avery D Ladymon, Pamela R Roberts, Alberto J de Armendi, Kar-Ming Fung and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Octascope: A Lightweight Pre-Trained Model for Optical Coherence Tomography.IEEE access : practical innovations, open solutions · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Recent Advances in Smart Epidural Spinal Needles.Sensors (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chen Wang *Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Paul Calle *School of Computer Science, University of Oklahoma, Norman, OK, 73019, USA.
Justin C Reynolds *School of Computer Science, University of Oklahoma, Norman, OK, 73019, USA.
Sam TonStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Feng YanStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Anthony M DonaldsonStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Avery D LadymonStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Pamela R RobertsDepartment of Anesthesiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Alberto J de ArmendiDepartment of Anesthesiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Kar-Ming FungDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Shashank S ShettarDepartment of Anesthesiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Chongle PanSchool of Computer Science, University of Oklahoma, Norman, OK, 73019, USA.
Qinggong TangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA. qtang@ou.edu.
University of Oklahoma · USUniversity of Oklahoma Health Sciences Center · US

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Michael S. Businelle · 2018 to 2026
$27.1M
TUMOR RESISTANCE MECHANISMS TO ANTI-VEGF THERAPY IN PROSTATE CANCER (Sukyung Woo)P20GM103639 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HANNAFON, BETHANY · 2012 to 2022
$21.3M
NCI NIH HHS P30 CA225520NCI NIH HHS P30CA225520NIGMS NIH HHS P20 GM103639NIGMS NIH HHS P20GM103639
6 · The paper itself

Abstract

Epidural anesthesia requires injection of anesthetic into the epidural space in the spine. Accurate placement of the epidural needle is a major challenge. To address this, we developed a forward-view endoscopic optical coherence tomography (OCT) system for real-time imaging of the tissue in front of the needle tip during the puncture. We tested this OCT system in porcine backbones and developed a set of deep learning models to automatically process the imaging data for needle localization. A series of binary classification models were developed to recognize the five layers of the backbone, including fat, interspinous ligament, ligamentum flavum, epidural space, and spinal cord. The classification models provided an average classification accuracy of 96.65%. During puncture, it is important to maintain a safe distance between the needle tip and the dura mater. Regression models were developed to estimate that distance based on the OCT imaging data. Based on the Inception architecture, our models achieved a mean absolute percentage error of 3.05% ± 0.55%. Overall, our results validated the technical feasibility of using this novel imaging strategy to automatically recognize different tissue structures and measure the distances ahead of the needle tip during the epidural needle placement.

Indexed as

Anesthesia, EpiduralDeep LearningAnimalsEpidural SpaceNeedlesSwineTomography, Optical Coherence

Identifiers

PMID35641505
PMCPMC9156706
OpenAlexW4281686306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.