Evidence map›Paper›PMID 35641217›Full record

ArticleThe oncologist2022

Safety of COVID-19 Vaccine in Patients with Cancer in a High-Volume Comprehensive Cancer Center.

Antonella Brunello, Valentina Guarneri, Marina Coppola, Matteo Bernardi, Ketti Ottolitri, Maria Grazia Ghi, Eleonora Mioranza, Federica Vianello, Michele Gottardi, Sara Lonardi and 1 more

Open access · goldAbstract read
In one paragraph

Article in The oncologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Antonella BrunelloMedical Oncology 1, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.ORCID 0000-0003-2583-5226
Valentina GuarneriDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Marina CoppolaPharmacy, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Matteo BernardiHealthcare Professions, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Ketti OttolitriRisk Management, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Maria Grazia GhiMedical Oncology 2, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Eleonora MioranzaMedical Oncology 2, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Federica VianelloRadiotherapy, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Michele GottardiOnco Hematology, Veneto Institute of Oncology IOV - IRCCS, Castelfranco Veneto, Italy.
Sara LonardiMedical Oncology 3, Veneto Institute of Oncology IOV - IRCCS, Castelfranco Veneto, Italy.
Vittorina ZagonelMedical Oncology 1, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Istituto Oncologico Veneto · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew data are available on the safety of COVID-19 vaccines in cancer patients undergoing active cancer-directed treatment. PATIENTS AND

methodsThis case series analyzes outcomes in terms of adverse events in 5297 patients undergoing anti-cancer treatment who were vaccinated with anti-SARS-CoV-2 Pfizer-BioNTech vaccine at a single cancer center from March 6, 2021 to May 9, 2021. Adverse events were retrieved from the national Italian pharmacovigilance platform (http://www.vigicovid.it).

resultsOf the 5297 patients treated for either solid tumors (87%) or onco-hematologic malignancies (13%) who were vaccinated, 8 adverse drug reactions (ADRs) were reported. One was a severe ADR and 7 were non-severe ADRs. Non-severe ADRs resolved within 48 hours.

conclusionBNT162b2 Pfizer-BioNTech vaccine was safely administered in the largest cohort of cancer patients reported to date.

Indexed as

COVID-19Drug-Related Side Effects and Adverse ReactionsHematologic NeoplasmsVaccinesAdverse Drug Reaction Reporting SystemsBNT162 VaccineCOVID-19 VaccinesHumansBNT162 VaccineCOVID-19 VaccinesVaccinescancerchemotherapyCOVID-19mRNAvaccine

Identifiers

PMID35641217
PMCPMC8895736
OpenAlexW4205258231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.