ArticleThe oncologist2022
Smoking Is Related to Worse Cancer-related Symptom Burden.
Article in The oncologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Prevalence of concurrent severe self-reported late symptoms and functional limitations in cancer survivors: a cross-sectional study of sociodemographic, clinical, and lifestyle associations.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Supportive Care Needs Among Pretreatment Head and Neck Cancer Patients According to Smoking Status: A Cross-Sectional Study With Nested Analyses.Laryngoscope investigative otolaryngology · 2026Article
- Integrating Sleep Health Education in Cancer Care: Prevalence and Correlates of Insomnia Among Omani Patients Undergoing Chemotherapy.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Nicotine and Cannabis Use in Adolescent and Young Adult Cancer Survivors: A Scoping Review.Journal of adolescent and young adult oncology · 2025Article
- Cigarette Smoking and Symptom Burden: Baseline Results From Nine ECOG-ACRIN Cancer Clinical Trials.Journal of pain and symptom management · 2025Article
- Rural and Appalachian cancer survivors' responses to tobacco use screening and tobacco treatment offer.Tobacco induced diseases · 2025Article
- Examining the Association between Abstinence from Smoking and Healthcare Costs among Patients with Cancer.Cancer prevention research (Philadelphia, Pa.) · 2024Article
- Association between smoking status, toxicity and survival in the checkpoint inhibitor immunotherapy.Frontiers in oncology · 2024Article
- A pharmacist-led community-based survey study: Determining the impact of the Covid-19 pandemic on actionable factors associated with worse cancer outcomes and cancer health disparities.Exploratory research in clinical and social pharmacy · 2023Article
- Tobacco use and cancer-related symptom burden: Analysis of the US Population Assessment of Tobacco and Health Study.Cancer · 2023Article
- Breast cancer: age incidence, hormone receptor status and family history in Najaf, Iraq.Journal of medicine and life · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCigarette smoking is related to greater cancer incidence, worse cancer-related clinical outcomes, and worse patient quality of life. Few studies have evaluated the role of smoking in patients' experiences of cancer-related symptom burden. This study examined relationships between smoking and total symptom burden as well as the incidence of severe symptoms among adult cancer patients. PATIENTS AND
methodsPatients at Moffitt Cancer Center completed self-report surveys as part of routine cancer care. Symptom burden was evaluated as the sum of individual symptom ratings (total symptom burden) and the number of symptoms rated severe (incidence of severe symptoms). Zero-inflated negative binomial modeling was used to evaluate the relationships between smoking status (ever vs never smoker) and symptom burden outcomes controlling for relevant sociodemographic and clinical covariates and accounting for the proportion of participants reporting no symptom burden.
resultsThis study included 12 571 cancer patients. More than half reported a history of cigarette smoking (n = 6771, 55%). Relative to never smokers, participants with a smoking history had 15% worse expected total symptom burden (ratio = 1.15, 95% confidence interval [CI] 1.11-1.20, P < .001) and 13% more expected severe symptoms (ratio = 1.13, 95% CI 1.05-1.21, P = .001) above and beyond the effects of relevant sociodemographic and clinical characteristics.
conclusionResults provide support that smoking is associated with worse cancer symptom burden. More research is needed to evaluate how smoking history (ie, current vs former smoker) and smoking cessation influence cancer symptom burden.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.