Evidence map›Paper›PMID 35641167›Full record

ReviewStem cells translational medicine2022

Blood Vessel Resident Human Stem Cells in Health and Disease.

David J Craig, Aaron W James, Yiyun Wang, Manuela Tavian, Mihaela Crisan, Bruno M Péault

Open access · goldAbstract readReview
In one paragraph

Review in Stem cells translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Black Chokeberry (Life (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
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  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

David J CraigCenter for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Aaron W JamesDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA.
Yiyun WangDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA.
Manuela TavianINSERM, IRFAC/UMR-S1113, Strasbourg, France.
Mihaela CrisanCenter for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Bruno M PéaultCenter for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Johns Hopkins University · USUniversity of Edinburgh · GBInserm · FROrthopaedic Hospital · US

Funding

Chief Scientist Office CGA/18/33Medical Research Council G1000816
6 · The paper itself

Abstract

The vascular wall is comprised of distinct layers controlling angiogenesis, blood flow, vessel anchorage within organs, and cell and molecule transit between blood and tissues. Moreover, some blood vessels are home to essential stem-like cells, a classic example being the existence in the embryo of hemogenic endothelial cells at the origin of definitive hematopoiesis. In recent years, microvascular pericytes and adventitial perivascular cells were observed to include multi-lineage progenitor cells involved not only in organ turnover and regeneration but also in pathologic remodeling, including fibrosis and atherosclerosis. These perivascular mesodermal elements were identified as native forerunners of mesenchymal stem cells. We have presented in this brief review our current knowledge on vessel wall-associated tissue remodeling cells with respect to discriminating phenotypes, functional diversity in health and disease, and potential therapeutic interest.

Indexed as

Mesenchymal Stem CellsPeripheral Blood Stem CellsEndothelial CellsHumansPericytesStem Cellsfibrosishematopoiesismesenchymal stem cellpericytetunica adventitiavascular endothelium

Identifiers

PMID35641167
PMCPMC8895497
OpenAlexW4206395028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.