Evidence map›Paper›PMID 35641131›Full record

ArticleJournal of animal science2022

Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.

Ge Yu, Shuli Ji, Yang Yun, Kang Cheng, Hao Zhang, Peilu Jia, Tian Wang, Lili Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ge YuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Shuli JiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Yang YunCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Kang ChengCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Hao ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Peilu JiaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Tian WangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.ORCID 0000-0002-9038-5009
Lili ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.
Nanjing Agricultural University · CN

Funding

Fundamental Research Funds for the Central Universities KJQN201935National Natural Science Foundation of China 31802101
6 · The paper itself

Abstract

This study investigated whether bamboo leaf extract (BLE) could improve the growth performance, antioxidant capacity, and inhibit hepatic apoptosis in suckling piglets. Sixty-four suckling piglets were orally gavaged with vehicle (CON group) or 100, 200, or 300 mg BLE/kg body weight (BL, BM, and BH groups) at 3 d of age for 21 d (n = 8). The results showed that BLE treatment had no effects on the growth performance (P > 0.05). Compared with the CON group, the BM and BH groups decreased (P < 0.05) the jejunal and hepatic malondialdehyde (MDA) contents. Supplementation with BLE increased antioxidant enzymes activities and the expressions of nuclear factor erythroid 2-related factor 2 (Nrf2) and several targeted genes in the jejunum and liver of suckling piglets. The hepatic apoptosis rate was lower (P < 0.05) in BLE treatment than in the CON group. Compared with the CON group, the BLE groups showed increased (P < 0.05) mRNA levels of B-cell-lymphoma protein 2 (BCL-2), whereas decreased (P < 0.05) BCL-2-associated X (BAX) and cysteine aspartate specific protease-3 (caspase-3) mRNA levels. The results of protein expressions of BCL-2 and caspase-3 were consistent with those of mRNA levels. Altogether, our results indicated that BLE intervention can improve the antioxidant capacity and inhibit hepatic apoptosis in suckling piglets.

Indexed as

AntioxidantsLiverPlant ExtractsAnimalsApoptosisCaspase 3Proto-Oncogene Proteins c-bcl-2RNA, MessengerSwineAntioxidantsCaspase 3Plant ExtractsProto-Oncogene Proteins c-bcl-2RNA, Messengerantioxidant capacityapoptosisbamboo leaf extractsuckling piglets

Identifiers

PMID35641131
PMCPMC9259598
OpenAlexW4282942809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.