Evidence map›Paper›PMID 35641098›Full record

ArticleOpen heart2022

Patient characteristics, short-term and long-term outcomes after incident heart failure admissions in a regional Australian setting.

Mohammed S Al-Omary, Tazeen Majeed, Hafssa Al-Khalil, Stuart Sugito, Mathew Clapham, Doan T M Ngo, John R Attia, Andrew J Boyle, Aaron L Sverdlov

Abstract read
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In one paragraph

Article in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammed S Al-OmaryCardiovascular Department, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.ORCID 0000-0002-5012-5106
Tazeen MajeedThe University of Newcastle, Callaghan, New South Wales, Australia.
Hafssa Al-KhalilJohn Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Stuart SugitoCardiovascular Department, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Mathew ClaphamHunter Medical Research Institute, Newcastle, New South Wales, Australia.
Doan T M NgoCollege of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
John R AttiaCollege of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
Andrew J BoyleCardiovascular Department, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Aaron L SverdlovCardiovascular Department, John Hunter Hospital, New Lambton Heights, New South Wales, Australia aaron.sverdlov@newcastle.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aims to (1) define the characteristics of patients with a first admission for heart failure (HF), stratified by type (reduced (HFrEF) vs preserved (HFpEF) ejection fraction) in a regional Australian setting; (2) compare the outcomes in terms of mortality and rehospitalisation and (3) assess adherence to the treatment guidelines.

methodsWe identified all index hospitalisations with HF to John Hunter Hospital and Tamworth Rural Referral Hospital in the Hunter New England Local Health District over a 12 months. We used the recent Australian HF guidelines to classify HFrEF and HFpEF and assess adherence to guideline-directed therapy. The primary outcome of the study was to compare short-term (1 year) and long-term all-cause mortality and the composite of all-cause hospitalisation or all-cause mortality of patients with HFrEF and HFpEF.

resultsThere were 664 patients who had an index HF admission to John Hunter and Tamworth hospitals in 2014. The median age was 80 years, 47% were female and 22 (3%) were Aboriginal. In terms of HF type, 29% had HFrEF, 37% had HFpEF, while the remainder (34%) did not have an echocardiogram within 1 year of admission and could not be classified. The median follow-up was 3.3 years. HFrEF patients were predominantly male (64%) and in 48% the aetiology was ischaemic heart disease. The 1-year all-cause mortality was 23% in HFpEF subgroup and 29% in HFrEF subgroup (p=0.15). Five-year mortality was 61% in HFpEF and HFrEF patients. Of the HFrEF patients, only 61% were on renin-angiotensin-aldosterone blockers, 74% were on β-blockers and 39% were on aldosterone antagonist.

conclusionHF patients are elderly and about evenly split between HFrEF and HFpEF. In this regional cohort, both HF types are associated with similar 1-year and 5-year mortality following incident HF hospitalisation. Echocardiography and guideline-directed therapies were underused.

Indexed as

Heart FailureAgedAged, 80 and overAustraliaFemaleHospitalizationHumansMaleStroke VolumeVentricular Function, LeftHeart FailureMedication AdherenceOutcome Assessment, Health CareQuality of Health Care

Identifiers

PMID35641098
PMCPMC9157343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.