Evidence map›Paper›PMID 35640537›Full record

ArticleIntervirology2022

Incidence of HPVs, EBV, and MMTV-Like Virus in Breast Cancer in Qatar.

Ishita Gupta, Reem Al-Sarraf, Hanan Farghaly, Semir Vranic, Ali A Sultan, Hamda Al-Thawadi, Ala-Eddin Al Moustafa, Halema F Al-Farsi

Open access · goldAbstract read
In one paragraph

Article in Intervirology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The viral origins of breast cancer.Infectious agents and cancer · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. HPV-Associated Breast Cancer: Myth or Fact?Pathogens (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ishita GuptaCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Reem Al-SarrafDepartment of Pathology, Hamad General Hospital, Doha, Qatar.
Hanan FarghalyDepartment of Pathology, Hamad General Hospital, Doha, Qatar.
Semir VranicCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Ali A SultanDepartment of Microbiology and Immunology, Weill Cornell Medicine - Qatar, Doha, Qatar.
Hamda Al-ThawadiCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Ala-Eddin Al MoustafaCollege of Medicine, QU Health, Qatar University, Doha, Qatar, aalmoustafa@qu.edu.qa.
Halema F Al-FarsiCollege of Medicine, QU Health, Qatar University, Doha, Qatar.
Qatar University · QAHamad General Hospital · QAWeill Cornell Medical College in Qatar · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHuman papillomaviruses (HPVs), Epstein-Barr virus (EBV), and mouse mammary tumor virus-like virus (MMTV-like virus) can be present and contribute to breast cancer development and progression. However, the role of these oncoviruses and their crosstalk in breast cancer is still unclear.

methodsWe explored the co-presence of high-risk HPVs, EBV, and MMTV-like virus in 74 breast cancer samples from Qatar using PCR.

resultsWe found the presence of HPV and EBV in 65% and 49% of our cancer sample cohorts; 47% of the samples are positive for both oncoviruses. The MMTV-like virus alone was detected in 15% of the samples with no significant association with clinicopathological features. The three oncoviruses were co-present in 14% of the cases; no significant association was noted between the co-presence of these viruses and the clinicopathological features.

conclusionDespite the presence of the oncoviruses, additional studies are necessary to understand their interactions in human breast carcinogenesis.

Indexed as

AlphapapillomavirusBreast NeoplasmsEpstein-Barr Virus InfectionsAnimalsFemaleHerpesvirus 4, HumanHumansIncidenceMammary Tumor Virus, MouseMicePapillomaviridaeQatarBreast cancerEpstein-Barr virusHuman papillomavirusMouse mammary tumor virus-like virusQatari population

Identifiers

PMID35640537
PMCPMC9677861
OpenAlexW4281744221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.