Evidence map›Paper›PMID 35640536›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

Ruxolitinib withdrawal complicating emergency aortic root replacement.

Malgorzata Maggie Szpytma, Damian Gimpel, Gareth Crouch, Jayme S Bennetts

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Malgorzata Maggie SzpytmaDepartment of Cardiothoracic Surgery, Flinders Medical Centre, Adelaide, SA, Australia.ORCID 0000-0002-5545-8794
Damian GimpelDepartment of Cardiothoracic Surgery, Flinders Medical Centre, Adelaide, SA, Australia.ORCID 0000-0001-7616-6945
Gareth CrouchDepartment of Cardiothoracic Surgery, Flinders Medical Centre, Adelaide, SA, Australia.ORCID 0000-0002-8756-9632
Jayme S BennettsDepartment of Cardiothoracic Surgery, Flinders Medical Centre, Adelaide, SA, Australia.ORCID 0000-0003-2398-8501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery.

Indexed as

Primary MyelofibrosisAortic ValveHumansNitrilesPyrazolesPyrimidinesNitrilesPyrazolesPyrimidinesruxolitinibAortic syndromeCardiac surgeryRuxolitinib

Identifiers

PMID35640536
PMCPMC9201970

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.