ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2022
Do Side Effects to the Primary COVID-19 Vaccine Reduce Intentions for a COVID-19 Vaccine Booster?
Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Vaccine acceptance in a future pandemic after COVID-19 and its decision drivers in Japan.NPJ vaccines · 2026Article
- Factors Associated With Self-Medication to Mitigate Vaccine Reactions After COVID-19 Vaccination: A Prospective Cohort Study.Pharmacoepidemiology and drug safety · 2026Article
- Exploring the relationship between experience of vaccine adverse events and vaccine hesitancy: A scoping review.Human vaccines & immunotherapeutics · 2025Article
- Hesitancy towards COVID-19 booster vaccine among healthcare workers in Bangladesh.BMC health services research · 2025Article
- Change in intention and hesitancy regarding COVID-19 vaccines in a cohort of adults in Quebec during the pandemic.Human vaccines & immunotherapeutics · 2024Article
- Factors associated with the COVID-19 booster vaccine intentions of young adults in the United States.Human vaccines & immunotherapeutics · 2024Article
- Active Surveillance for Safety Monitoring of XBB.1.5-Containing COVID-19 mRNA Vaccines in Korea.Journal of Korean medical science · 2024Article
- Article
- The Nocebo Effect.Annual review of pharmacology and toxicology · 2024Review
- Expectations and Prior Experiences Associated With Adverse Effects of COVID-19 Vaccination.JAMA network open · 2023Article
- Psychological factors associated with reporting side effects following COVID-19 vaccination: A prospective cohort study (CoVAccS - Wave 3).Journal of psychosomatic research · 2023Article
- Drivers of the Intention to Receive a COVID-19 Booster Vaccine: Insights from the UK and Australia.Vaccines · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVaccines are being administered worldwide to combat the COVID-19 pandemic. Vaccine boosters are essential for maintaining immunity and protecting against virus variants. The side effects of the primary COVID-19 vaccine (e.g., headache, nausea), however, could reduce intentions to repeat the vaccination experience, thereby hindering global inoculation efforts. PURPOSE: The aim of this research was to test whether side effects of a primary COVID-19 vaccine relate to reduced intentions to receive a COVID-19 booster. The secondary aim was to test whether psychological and demographic factors predict booster intentions.
methodsSecondary data analyses were conducted on a U.S. national sample of 551 individuals recruited through the online platform Prolific. Key measures in the dataset were side effects reported from a primary COVID-19 vaccination and subsequent intentions to receive a booster vaccine. Psychological and demographic variables that predicted primary vaccination intentions in prior studies were also measured.
resultsBooster intentions were high. COVID-19 booster vaccine intentions were uncorrelated with the number of side effects, intensity of side effects, or occurrence of an intense side effect from the primary COVID-19 vaccine. Correlational and regression analyses indicated intentions for a booster vaccination increased with positive vaccination attitudes, trust in vaccine development, worry about the COVID-19 pandemic, low concern over vaccine side effects, and democratic political party affiliation.
conclusionsSide effects of a primary COVID-19 vaccine were not directly associated with lower intentions to receive a booster of the COVID-19 vaccine early in the pandemic. However, many variables that predict primary vaccination intentions also predict booster intentions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.