ArticleJournal of cognitive neuroscience2022
The Neuroanatomy of Speech Processing: A Large-scale Lesion Study.
Article in Journal of cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Mapping the neural patterns of verbal repetition: an activation likelihood estimation meta-analysis.Brain structure & function · 2026Pooled it
- Article
- Audiovisual Synchrony in Left-hemisphere Brain-lesioned Individuals with Aphasia.Journal of cognitive neuroscience · 2025Article
- Cortical connectivity in speech and sensory networks associated with childrens' listening and attention disorders.medRxiv : the preprint server for health sciences · 2025Article
- Acute temporal lesions are associated with phonological word verification errors.Brain network disorders · 2025Article
- Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke.Brain : a journal of neurology · 2025Article
- Converging and conflicting evidence for left temporal lobe regions in acoustic-phonetic perception.Brain : a journal of neurology · 2025Article
- How Can Graph Theory Inform the Dual-stream Model of Speech Processing? A Resting-state Functional Magnetic Resonance Imaging Study of Stroke and Aphasia Symptomology.Journal of cognitive neuroscience · 2025Article
- A Biopsychosocial Overview of Speech Disorders: Neuroanatomical, Genetic, and Environmental Insights.Biomedicines · 2025Review
- Central alterations of brain networks in patients with optic neuritis: a resting state fMRI study.International journal of ophthalmology · 2025Article
- Recollection and familiarity support auditory working memory in a manner analogous to visual working memory.Cognition · 2025Article
- Auditory discrimination learning differentially modulates neural representation in auditory cortex subregions and inter-areal connectivity.Cell reports · 2024Article
- Perceiving and misperceiving speech: lexical and sublexical processing in the superior temporal lobes.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Auditory-motor synchronization and perception suggest partially distinct time scales in speech and music.Communications psychology · 2024Article
- Sound-localization-related activation and functional connectivity of dorsal auditory pathway in relation to demographic, cognitive, and behavioral characteristics in age-related hearing loss.Frontiers in neuroscience · 2024Article
- Evoking artificial speech perception through invasive brain stimulation for brain-computer interfaces: current challenges and future perspectives.Frontiers in neuroscience · 2024Review
- Preserved Gray Matter Volume in the Left Superior Temporal Gyrus Underpins Speech-in-Noise Processing in Middle-Aged Adults.The journal of international advanced otology · 2024Article
- Insights into epileptic aphasia: Intracranial recordings in a child with a left insular ganglioglioma.Epilepsy & behavior reports · 2024Article
- Vagal Nerve Activity and Short-Term Clinical Outcomes after Stroke: What Is Left May Not Be Right.Journal of clinical medicine · 2023Article
- Explaining flexible continuous speech comprehension from individual motor rhythms.Proceedings. Biological sciences · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
The neural basis of language has been studied for centuries, yet the networks critically involved in simply identifying or understanding a spoken word remain elusive. Several functional-anatomical models of critical neural substrates of receptive speech have been proposed, including (1) auditory-related regions in the left mid-posterior superior temporal lobe, (2) motor-related regions in the left frontal lobe (in normal and/or noisy conditions), (3) the left anterior superior temporal lobe, or (4) bilateral mid-posterior superior temporal areas. One difficulty in comparing these models is that they often focus on different aspects of the sound-to-meaning pathway and are supported by different types of stimuli and tasks. Two auditory tasks that are typically used in separate studies-syllable discrimination and word comprehension-often yield different conclusions. We assessed syllable discrimination (words and nonwords) and word comprehension (clear speech and with a noise masker) in 158 individuals with focal brain damage: left (n = 113) or right (n = 19) hemisphere stroke, left (n = 18) or right (n = 8) anterior temporal lobectomy, and 26 neurologically intact controls. Discrimination and comprehension tasks are doubly dissociable both behaviorally and neurologically. In support of a bilateral model, clear speech comprehension was near ceiling in 95% of left stroke cases and right temporal damage impaired syllable discrimination. Lesion-symptom mapping analyses for the syllable discrimination and noisy word comprehension tasks each implicated most of the left superior temporal gyrus. Comprehension but not discrimination tasks also implicated the left posterior middle temporal gyrus, whereas discrimination but not comprehension tasks also implicated more dorsal sensorimotor regions in posterior perisylvian cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.