ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023
Severe Acute Respiratory Syndrome Coronavirus 2 Incidence and Risk Factors in a National, Community-Based Prospective Cohort of US Adults.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Long COVID longitudinal symptoms burden clusters within a national community-based cohort.BMC infectious diseases · 2026Article
- Long COVID Longitudinal Symptoms Burden Clusters Within A National Community-Based Cohort.medRxiv : the preprint server for health sciences · 2025Article
- Natural History of Self-reported Symptoms Following SARS-CoV-2 Infection: A Target Trial Emulation in a Prospective Community-Based Cohort.medRxiv : the preprint server for health sciences · 2025Article
- Barriers to initial COVID-19 booster among US adults who completed a primary vaccine series in the CHASING COVID cohort, September 2021-October 2022.American journal of epidemiology · 2025Article
- Sliding down the socioeconomic health gradient of COVID-19 in New York City: multinomial regression analyses of disproportionate financial hardship for Black, Latino, and Asian residents and households with children.Frontiers in public health · 2025Article
- Oral COVID-19 Antiviral Uptake Among a Highly Vaccinated US Cohort of Adults With SARS-CoV-2 Infection Between December 2021 and October 2022.Open forum infectious diseases · 2024Article
- Seroincidence of SARS-CoV-2 infection prior to and during the rollout of vaccines in a community-based prospective cohort of U.S. adults.Scientific reports · 2024Article
- Persistence of antibody responses to COVID-19 vaccines among participants in the COVID-19 Community Research Partnership.Vaccine: X · 2023Article
- Seroincidence of SARS-CoV-2 infection prior to and during the rollout of vaccines in a community-based prospective cohort of U.S. adults.medRxiv : the preprint server for health sciences · 2023Article
- Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States.Emerging infectious diseases · 2022Article
- Understanding the social determinants of health and genetic factors contributing to the differences observed in COVID-19 incidence and mortality between underrepresented and other communities.Journal of the National Medical Association · 2022Review
- Household factors and the risk of severe COVID-like illness early in the U.S. pandemic.PloS one · 2022Article
- COVID-19 Infection Risk Among Previously Uninfected Adults: Development of a Prognostic Model.Health services research and managerial epidemiologyArticle
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15 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundProspective cohort studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) incidence complement case-based surveillance and cross-sectional seroprevalence surveys.
methodsWe estimated the incidence of SARS-CoV-2 infection in a national cohort of 6738 US adults, enrolled in March-August 2020. Using Poisson models, we examined the association of social distancing and a composite epidemiologic risk score with seroconversion. The risk score was created using least absolute shrinkage selection operator (LASSO) regression to identify factors predictive of seroconversion. The selected factors were household crowding, confirmed case in household, indoor dining, gathering with groups of ≥10, and no masking in gyms or salons.
resultsAmong 4510 individuals with ≥1 serologic test, 323 (7.3% [95% confidence interval (CI), 6.5%-8.1%]) seroconverted by January 2021. Among 3422 participants seronegative in May-September 2020 and retested from November 2020 to January 2021, 161 seroconverted over 1646 person-years of follow-up (9.8 per 100 person-years [95% CI, 8.3-11.5]). The seroincidence rate was lower among women compared with men (incidence rate ratio [IRR], 0.69 [95% CI, .50-.94]) and higher among Hispanic (2.09 [1.41-3.05]) than white non-Hispanic participants. In adjusted models, participants who reported social distancing with people they did not know (IRR for always vs never social distancing, 0.42 [95% CI, .20-1.0]) and with people they knew (IRR for always vs never, 0.64 [.39-1.06]; IRR for sometimes vs never, 0.60 [.38-.96]) had lower seroconversion risk. Seroconversion risk increased with epidemiologic risk score (IRR for medium vs low score, 1.68 [95% CI, 1.03-2.81]; IRR for high vs low score, 3.49 [2.26-5.58]). Only 29% of those who seroconverted reported isolating, and only 19% were asked about contacts.
conclusionsModifiable risk factors and poor reach of public health strategies drove SARS-CoV-2 transmission across the United States.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.