Evidence map›Paper›PMID 35639492›Full record

ArticleAnnals of medicine2022

Low Psoas-Muscle index is associated with decreased survival in hepatocellular carcinoma treated with transarterial chemoembolization.

Jin-Xing Zhang, Hai-Tao Yan, Ye Ding, Jin Liu, Sheng Liu, Qing-Quan Zu, Hai-Bin Shi

Registry-linked trialAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06829290 (Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06829290 recruitingnot on this mapstarted 2024, after this paper: background citation

Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers

Typeobservational_patient_registrySponsorUniversitatsmedizin Mainz - 1. Medizinische KlinikRan2024 to 2028Enrolled200ConditionsLiver Cirrhosis, Cancer, Cachexia, SarcopeniaArmsUltrasound
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. [The value of the nutritional assessment index or score in prognostic evaluation for patients with liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin-Xing ZhangDepartment of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Hai-Tao YanDepartment of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Ye DingDepartment of Maternal, Child and Adolescent Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Jin LiuDepartment of Clinical Medicine Research Institution, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Sheng LiuDepartment of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Qing-Quan ZuDepartment of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.ORCID 0000-0001-7359-0791
Hai-Bin ShiDepartment of Interventional Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSkeletal muscle index (SMI) is a promising predictor of clinical outcomes in patients with malignant diseases. As a simpler surrogate of sarcopenia-psoas muscle index (PMI), its predict value for overall survival (OS) after transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) has not been reported. To determine if changes in the PMI predicted OS in individuals with HCC treated with TACE. PATIENTS AND

methodsA retrospective analysis was performed in HCC patients treated with TACE between January 2018 and March 2019. The survival curve according to PMI was estimated by the Kaplan-Meier method and then compared by the log-rank test. Cox proportional hazards models were conducted to identify the prognostic factors for OS. Furthermore, the predictive abilities of PMI and SMI were compared by using Harrell's concordance index (C-index).

resultsTwo hundred and twenty-eight patients (175 men, mean age 59 ± 11 years) were analysed. The OS was less in patients with low PMI than those with high PMI (median OS: 16.9 vs. 38.5 months,

conclusionPMI is a simple tool to predict OS in HCC patients treated with TACE. The predictive ability of PMI is comparable to that of SMI. Key messagesLow psoas-muscle index is associated with decreased overall survival in hepatocellular carcinoma treated with transarterial chemoembolization (TACE).Psoas-muscle index has advantages of being faster and easier to acquire, which thus makes it more likely to achieve widespread clinical application.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsAgedHumansMaleMiddle AgedPsoas MusclesRetrospective StudiesCarcinomachemoembolizationhepatocellularsarcopeniasurvival analysistherapeutic

Identifiers

PMID35639492
PMCPMC9176702

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.