Evidence map›Paper›PMID 35639457›Full record

ArticleJMIR formative research2022

Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study.

Mariette Abrahams, Rochez O'Grady, Janne Prawitt

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04245254 (GutMe!), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04245254 nacompletednot on this map

GutMe!: IBS and Collagen Protein Powder an Interventional Study

TypeinterventionalSponsorProofPilotRan2020 to 2020Enrolled50ConditionsIrritable Bowel Syndrome, Irritable Bowel, IrritArmsCollagen Protien Powder
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariette AbrahamsQina Ltd, Olhao, Portugal.ORCID https://orcid.org/0000-0003-2393-2487
Rochez O'GradyQina Ltd, Olhao, Portugal.ORCID https://orcid.org/0000-0001-6121-6567
Janne PrawittRousselot BV, Gent, Belgium.ORCID https://orcid.org/0000-0001-6803-0079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of dietary collagen on managing digestive symptoms is currently lacking in the literature.

objectiveTo gain a better understanding of this issue, we conducted a 2-phase mixed methods study.

methodsPhase 1 was a mixed methods design to explore current attitude and practice among consumers and health care practitioners. The findings were used to design an 8-week phase 2 digital study called Gutme! conducted in the United States in healthy female volunteers (BMI>25 kg/m

resultsPhase 1 revealed that consumer awareness of collagen for digestive health is low (64/204, 31.4%). Among the dietitians prescribing collagen for their patients, the most common dosage was 20 g a day with notable effects after 6 weeks of intake. Within the phase 2 study, of the 40 recruited participants, 14 (35%) completed the full course of supplementation. The findings indicate that 93% (13/14) of those who completed the study experienced a reduction in digestive symptoms, which included bloating.

conclusionsA mixed methods digital study design is feasible and acceptable for collecting relevant data in a real-life setting. The use of a 20 g daily collagen peptide supplement may reduce bloating and improve mild digestive symptoms in otherwise healthy female adults in the absence of any other dietary or lifestyle interventions.

trial registrationClinicalTrials.gov NCT04245254; https://clinicaltrials.gov/ct2/show/NCT04245254.

Indexed as

bloatingcollagen hydrolysatescollagen peptidesdigestive symptomsdigital studyguthealth care professionalsmicrobiomemobile phonePeptantechnology

Identifiers

PMID35639457
PMCPMC9198822
OpenAlexW4224295451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.