Evidence map›Paper›PMID 35639300›Full record

ArticleCell biology and toxicology2023

PCBP1-mediated regulation of WNT signaling is critical for breast tumorigenesis.

Zhao-Ying Yang, Wen-Long Zhang, Cheng-Wei Jiang, Guang Sun

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biology and toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Cysteine reactivity profiling identifies host regulators ofbioRxiv : the preprint server for biology · 2025
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhao-Ying YangDepartment of Breast Surgery, China-Japan Union Hospital of Jilin University, No.126, Xiantai Street, Changchun, Jilin, 130033, China.
Wen-Long ZhangDepartment of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Cheng-Wei JiangDepartment of Pathology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Guang SunDepartment of Breast Surgery, China-Japan Union Hospital of Jilin University, No.126, Xiantai Street, Changchun, Jilin, 130033, China. sunguangky@jlu.edu.cn.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of expression or protein kinase B (Akt1)-mediated post-translational modification of the RNA binding protein Poly r(C) binding protein 1 (PCBP1) is closely related to metastatic advancement of breast cancer. However, the role of PCBP1 in tumorigenesis is not completely defined. Using a xenograft orthotopic model of breast tumorigenesis (4T1-Pcbp1

Indexed as

Breast NeoplasmsWnt Signaling PathwayAnimalsCarcinogenesisCell Transformation, NeoplasticDNA-Binding ProteinsFemaleHumansMiceRNA-Binding ProteinsTumor MicroenvironmentDNA-Binding ProteinsPCBP1 protein, humanPcbp1 protein, mouseRNA-Binding ProteinsEffector T cellsGSK3βPCBP1Regulatory T cellsWNT

Identifiers

PMID35639300
OpenAlexW4281627433

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.