Evidence map›Paper›PMID 35639262›Full record

ReviewCurrent nutrition reports2022

Intermittent Fasting in Cancer: a Role in Survivorship?

Eleah Stringer, Julian J Lum, Nicol Macpherson

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05708326 (Does Timing Matter? A Case Crossover Study of Intermittent Fasting in Patients With CLL/SLL at BC Cancer- Victoria), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05708326 nacompletednot on this mapstarted 2023, after this paper: background citation

Does Timing Matter? A Case Crossover Study of Intermittent Fasting in Patients With CLL/SLL at BC Cancer- Victoria

TypeinterventionalSponsorBritish Columbia Cancer AgencyRan2023 to 2023Enrolled6ConditionsChronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)Arms5:2 Method (intermittent fasting regimen), 16/8 Method (intermittent fast regimen)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eleah StringerOncology Nutrition, BC Cancer - Victoria, 2410 Lee Ave, Victoria, BC, V8R 6V5, Canada. Eleah.stringer@bccancer.bc.ca.ORCID 0000-0002-9865-367X
Julian J LumTrev and Joyce Deeley Research Centre, BC Cancer - Victoria, Victoria, Canada.
Nicol MacphersonMedical Oncology, BC Cancer - Victoria, Victoria, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo discuss the historical development of intermittent fasting, its potential underlying mechanisms, and the state of clinical trials, and to reflect on considerations for practice and future recommendations. RECENT

findingsPreclinical studies consistently show the robust disease-modifying efficacy of intermittent fasting in various metabolic diseases which may hold implications for cancer prevention and survivorship. Twenty-one clinical trials have or are being conducted on fasting in cancer, utilizing various fasting regimens across different tumor types as a stand-alone intervention or in adjunct to anticancer treatment, with heterogenous outcome variables. Though there are no known, reproducible diets, to cure or prevent cancer recurrence, preliminary research on the underlying mechanisms, tolerance, and safety of intermittent fasting in cancer warrants further investigation. The inherent flexibility of intermittent fasting to accommodate all types of diets is of necessity in oncology.

Indexed as

Metabolic DiseasesNeoplasmsFastingHumansSurvivorshipCancer survivorshipIntermittent fastingOncologyTime-restricted feeding

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.