Evidence map›Paper›PMID 35639217›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Late epileptic seizures following cerebral venous thrombosis: a systematic review and meta-analysis.

Sara Gasparini, Sabrina Neri, Francesco Brigo, Vittoria Cianci, Anna Mammì, Angelo Pascarella, Lucia Manzo, Paolo Benna, Pasquale Striano, Tommaso Martino and 14 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Reducing the global burden of cerebral venous thrombosis: An international research agenda.International journal of stroke : official journal of the International Stroke Society · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 13 institutions in 2 countries.

Sara GaspariniDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Sabrina NeriDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Francesco BrigoDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Merano, Italy.
Vittoria CianciRegional Epilepsy Centre at Great Metropolitan Hospital, Via Melacrino, Reggio Calabria, Italy.
Anna MammìDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Angelo PascarellaDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Lucia ManzoDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Paolo BennaNeuroscience Department, University of Turin, Turin, Italy.
Pasquale StrianoDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.
Tommaso MartinoEpilepsy Centre, Clinic of Nervous System Diseases, University of Foggia, Ospedali Riuniti, Foggia, Italy.
Michele RomoliNeurology Unit and Stroke Unit, Ospedale "Bufalini", Cesena, Italy.
Lorenzo MuccioliDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Annacarmen NiloClinical Neurology Unit, Santa Maria della Misericordia University Hospital, Udine, Italy.
Mariarosaria ValenteClinical Neurology Unit, Santa Maria della Misericordia University Hospital, Udine, Italy.
Claudia CagnettiNeurology Unit, Università Politecnica Delle Marche, Ancona, Italy.
Angelo LabateNeurology Unit, Department of BIOMORF, University of Messina, Messina, Italy.
Antonio GambardellaDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Francesco PisaniDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Sara CasciatoIRCCS Neuromed, Pozzilli, Italy.
Giancarlo Di GennaroIRCCS Neuromed, Pozzilli, Italy.
Vincenzo BelcastroNeurology Unit, Maggiore Hospital, ASST Lodi, Lodi, Italy.
Umberto AgugliaDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Edoardo FerlazzoDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy. ferlazzo@unicz.it.ORCID http://orcid.org/0000-0003-3531-8337
Epilepsy Study Group of the Italian Neurological Society
Magna Graecia University · ITIstituto Neurologico Mediterraneo · ITUniversity of Messina · ITAziende Socio Sanitarie Territoriale LodiIstituto Giannina Gaslini · ITKrankenhaus Meran · ITMarche Polytechnic University · ITOspedale “M. Bufalini” di Cesena · ITOspedale Santa Maria della Misericordia di Udine · ITUniversity of Bologna · ITUniversity of Foggia · ITUniversity of Turin · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying late epileptic seizures (LS) following cerebral venous thrombosis (CVT) can be useful for prognosis and management. We systematically reviewed the literature to identify risk factors for LS due to CVT.

methodsWe systematically searched PubMed, Scholar, and Scopus databases (May 2021) to identify studies reporting data on prevalence and risk factors for CVT-LS. The methodological quality was assessed with the Ottawa-Newcastle Scale. The risk of developing CVT-LS was summarized in meta-analyses and expressed as odds ratio (OR) and corresponding 95% confidence intervals (CIs) using random-effects models.

resultsOut of the 332 records retrieved, four studies were eventually included with a total of 1309 patients with CVT and 142 (11%) with CVT-LS. The most relevant predictors of CVT-LS were symptomatic seizures (OR 5.66, 95% CI 3.83-8.35), stupor/coma (OR 6.81, 95% CI 1.18-39.20), focal neurologic signs (OR 6.81, 95% CI 1.18-39.2), hemorrhagic component (OR 3.52, 95% CI 2.45-5.06), and superior sagittal sinus involvement (OR 1.52, 95% CI 1.04-2.21).

conclusionThere are several risk factors for CVT-LS that should be considered in clinical practice. Further high-quality studies are warranted to develop predictive models for individualized risk stratification and prediction of CVT-LS.

Indexed as

EpilepsyIntracranial ThrombosisVenous ThrombosisHumansRisk FactorsSeizuresCerebral venous thrombosisEpilepsyFocal signsHemorrhagePredictors

Identifiers

PMID35639217
PMCPMC9153875
OpenAlexW4281674444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.