SynthesisJournal of neurology2022
Ultrasonography for the diagnosis of carpal tunnel syndrome: an umbrella review.
Synthesis in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 71 citations in OpenAlex.
- Clinical outcomes of low versus high intensity laser therapy in patients with subacute carpal tunnel syndrome: A randomized, single-blinded, controlled trial.Lasers in medical science · 2026Trial
- Effects of radial extracorporeal shock wave and kinesio taping on pain, quality of life, hand function and ultrasonographic measurement of median nerve cross-sectional area in patients with carpal tunnel syndrome: a single-blind randomized controlled trial.Irish journal of medical science · 2025Trial
- Evaluation of Splint and Exercise Interventions for Carpal Tunnel Syndrome: Insights from Ultrasonographic Measurements.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Effects of high-intensity laser therapy on pain, functional status, hand grip strength, and median nerve cross-sectional area by ultrasonography in patients with carpal tunnel syndrome.Lasers in medical science · 2023Trial
- Ultrasound-guided needle knife release of the transverse carpal ligament for carpal tunnel syndrome: a prospective case series study.Quantitative imaging in medicine and surgery · 2026Article
- Contrast-enhanced magnetic resonance neurography aids in diagnosis and grading of carpal tunnel syndrome: a preliminary study.La Radiologia medica · 2026Article
- Ultrasound-guided versus landmark-guided corticosteroid injections for carpal tunnel syndrome: an overview and cross-sectional analysis of overlapping meta-analyses of randomized controlled trials.European radiology · 2026Article
- Artificial intelligence in ultrasound imaging for carpal tunnel syndrome: what clinicians need to know.Journal of medical ultrasonics (2001) · 2026Review
- Median neuropathy after open reduction and internal fixation: when implant proximity is not the culprit.Journal of Yeungnam medical science · 2026Article
- Ultrasound-guided acupotomy: a paradigm shift toward precision and safety in carpal tunnel syndrome therapy.Frontiers in medicine · 2026Article
- Relationships between serum mercaptoalbumin/non-mercaptoalbumin ratio, 25(OH)D level, symptom severity, functional status and median nerve cross-sectional area in carpal tunnel syndrome.Turkish journal of physical medicine and rehabilitation · 2025Article
- Evaluation of Clemastine's Effects on Clinical and Electrodiagnostic Parameters in Individuals With CTS: A Preliminary Placebo-Controlled Double-Blind RCT.Archives of rehabilitation research and clinical translation · 2025Article
- Umbrella Reviews: Concepts, Methodological Frameworks, and Step-by-Step Implementation.Journal of evidence-based medicine · 2025Review
- Median Nerve Diameter Ratio on Ultrasound as a Complementary Tool to Electrodiagnostic Testing in Carpal Tunnel Syndrome.Diagnostics (Basel, Switzerland) · 2025Article
- Grip Force Modulation on Median Nerve Morphology Changes.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Ultrasound Characteristics of Carpal Tunnel Syndrome in the Spanish Population.Journal of clinical ultrasound : JCU · 2025Observational
- The Median Nerve Displays Adaptive Characteristics When Exposed to Repeated Pinch Grip Efforts of Varying Rates of Force Development: An Ultrasonic Investigation.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Effectiveness of Comprehensive Video Datasets: Toward the Development of an Artificial Intelligence Model for Ultrasonography-Based Severity Diagnosis of Carpal Tunnel Syndrome.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Diagnostic Dilemmas in Carpal Tunnel Syndrome and Cervical Spine Disorders: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Evaluating Various Ultrasound Criteria for Determining Carpal Tunnel Syndrome Severity.Radiology research and practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundNumerous sonographic modalities and parameters have been used to diagnose carpal tunnel syndrome (CTS), with varying accuracy. Our umbrella review aimed to summarize the evidence from systematic reviews and meta-analyses regarding the use of ultrasound imaging to diagnose CTS.
methodsSystematic reviews and meta-analyses meeting the inclusion criteria were searched in PubMed, Embase, Medline, Web of Science, and Cochrane databases from inception to March 2022. Critical appraisal, data extraction, and synthesis were performed in accordance with the criteria for conducting an umbrella review.
resultsSixteen reviews were included. Three reviews were classified as high quality, one as moderate, four as low, and eight as critically low. The cross-sectional area (CSA) of the median nerve at the carpal tunnel inlet demonstrated the best reliability and diagnostic accuracy among multiple parameters. A cutoff CSA value of 9-10.5 mm
conclusionsSonography is a reliable tool to diagnose CTS, with inlet CSA being the most robust parameter. Sonoelastography and Doppler ultrasound can serve as auxiliary tools to confirm CTS diagnoses. Further studies are needed to expand the use of sonography for diagnosing CTS, especially in the presence of concomitant neuromuscular disease(s).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.