Evidence map›Paper›PMID 35639002›Full record

ArticleMicrobiology spectrum2022

Detection of Salmonella Typhi in Bile by Quantitative Real-Time PCR.

Ellen E Higginson, Joseph Nkeze, Jasnehta Permala-Booth, Irene N Kasumba, Rosanna Lagos, Juan Carlos Hormazabal, Alexander Byrne, Gad Frankel, Myron M Levine, Sharon M Tennant

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Ellen E Higginson *Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-9218-1627
Joseph Nkeze *Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jasnehta Permala-BoothCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Irene N KasumbaCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Rosanna LagosCentro de Vacunas en Desarollo, Hospital de Ninos Roberto del Rio, Santiago, Chile.
Juan Carlos HormazabalInstituto de Salud Publica de Chile, Santiago, Chile.
Alexander ByrneMRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, Londongrid.7445.2, United Kingdom.
Gad FrankelMRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, Londongrid.7445.2, United Kingdom.ORCID 0000-0002-0046-1363
Myron M LevineCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sharon M TennantCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0651-5748
University of Maryland, Baltimore · USImperial College London · GBHospital Roberto del Rio · CLInstituto de Salud Pública de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In countries where the incidence of typhoid fever is high, fecal material from short-term carriers of Salmonella Typhi contaminates inadequately treated water supplies. As treated water supplies and improved sanitation become available, chronic (mainly gallbladder) carriers of S. Typhi become important. The objective of this study was to develop a method for detection of S. Typhi in bile by quantitative real-time PCR (qPCR) in patients undergoing cholecystectomy. We evaluated sensitivity and specificity of probesets that target

Indexed as

Salmonella typhiTyphoid FeverBileCefazolinCeftriaxoneHumansReal-Time Polymerase Chain ReactionCefazolinCeftriaxonebilecarrierdetectiongall bladdertyphoid

Identifiers

PMID35639002
PMCPMC9241738
OpenAlexW4281771810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.