ArticleMicrobiology spectrum2022
Impact of the SARS-CoV-2 Pandemic on the Prevalence and Incidence of Gastrointestinal Viruses in Children up to Five Years Old: a Retrospective Cohort Study.
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Disease burden of norovirus-associated diarrhea among children under 5 years old in China: a meta-analysis.BMC infectious diseases · 2025Pooled it
- A systematic review and meta-analysis of the global prevalence of human enteric adenovirus infections.Journal of infection and public health · 2025Pooled it
- Gastrointestinal pathogens in paediatric patients with diarrhoea during the COVID-19 pandemic in Spain: a multicentre molecular-based prospective study.European journal of pediatrics · 2026Article
- Paediatric infection hospital admissions in England before, during, and after the COVID-19 pandemic.Epidemiology and infection · 2026Article
- Global Impact of COVID-19 Pandemic on Gastrointestinal Infections: A Scoping Review.Foodborne pathogens and disease · 2025Article
- Molecular detection and characterization of human bocavirus in environmental waters in Thailand from 2020 to 2022.One health (Amsterdam, Netherlands) · 2025Article
- Incidence of biliary atresia in the United States before and during the COVID-19 pandemic.Journal of pediatric gastroenterology and nutrition · 2025Article
- Pediatric Rotavirus Hospitalization Rates in the Military Health System Before and During the COVID-19 Pandemic.Vaccines · 2025Article
- Impact of the SARS-CoV-2 Pandemic on the Prevalence and Incidence of Enteric Protozoa in a Spanish Tertiary-Care Hospital and a Referral Center for Tropical Diseases, 2019-2023.Medical sciences (Basel, Switzerland) · 2025Article
- Children hospitalised with gastroenteritis before and during the COVID-19 pandemic.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Impact of COVID-19 pandemic on clinical features of benign convulsions with mild gastroenteritis.Clinical and experimental pediatrics · 2024Article
- [Impact of the pandemic on various infectious diseases with different epidemiological patterns of seasonality, transmission and age].Revista espanola de salud publica · 2024Article
- Characteristics of Gastroenteritis Outbreaks Investigated in Singapore: 2018-2021.International journal of environmental research and public health · 2024Article
- Temporal changes in the positivity rate of common enteric viruses among paediatric admissions in coastal Kenya, during the COVID-19 pandemic, 2019-2022.Gut pathogens · 2024Article
- Differences in epidemiology of enteropathogens in children pre- and post-rotavirus vaccine introduction in Kilifi, coastal Kenya.Gut pathogens · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim is determining the impact of non-pharmaceutical measures (NPIs) against SARS-CoV-2 in the incidence and prevalence of gastrointestinal viruses (GV) in children. Demographic, analytical, and clinical data of children from which samples were received at the Hospital Universitario La Paz (Madrid, Spain) and that had a gastrointestinal infection with a positive sample through multiplex-PCR for GV were collected. The time periods included were prepandemic (P1): March 14, 2019 to March 14, 2020 and pandemic (P2): March 15, 2020 to March 15, 2021. The global prevalence, relative incidence (RI, per 1,000 admissions) and absolute incidence (AI, per 100,000 population) of GV were compared for both time periods. The prevalence of GV versus SARS-CoV-2 was determined for P2. Seven-hundred and 50 out of 2,547 children analyzed in P1 and 106 out of 1,368 in P2 were positive by PCR for GV (46.3% decrease in P2). Prevalence and RI of GV declined in P2, except for the RI of rotavirus. Adenovirus showed the largest decreased of prevalence and RI (100%), followed by sapovirus. Astrovirus reduction was less pronounced (3.1% versus 0.4%). Norovirus was the most frequent virus in both time periods and its prevalence and RI also decreased in P2 (15.2% versus 4.7% and 3.40 versus 1.74, respectively). Rotavirus had the smallest decrease in prevalence (2.6% versus 2.5%), and its RI increased during P2 from 0.7 to 0.93. After removing the rotavirus vaccine strains from the analysis, the prevalence and RI decreased during P2 (2.1% to 0.7% and 0.5 to 0.3, respectively). The AI decreased during P2 in all GV, and the prevalence of SARS-CoV-2 and GV was inversely proportional over time. Prevalence and incidence of GV have decreased during the pandemic, probably due to the implementation of NPIs against this virus and the reduction of health care attention to infections other than COVID-19. The differences in the decrease of prevalence and incidence for each virus may be explained by differences in the transmission and the resistance in the environment. Prevalence and RI of rotavirus might be biased since the PCR used detects both the infecting and the vaccine strains.
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