Evidence map›Paper›PMID 35638845›Full record

ArticleApplied and environmental microbiology2022

The c-di-GMP Phosphodiesterase PipA (PA0285) Regulates Autoaggregation and Pf4 Bacteriophage Production in Pseudomonas aeruginosa PAO1.

Yu-Ming Cai, Kai-Wei Yu, Ji-Hong Liu, Zhao Cai, Zun-Hao Zhou, Yang Liu, Tian-Fu Wang, Liang Yang

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  4. Transcriptional profiling ofFrontiers in microbiology · 2026
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  12. A Library of Promoter-Applied and environmental microbiology · 2023
    Article
  13. Article
  14. Genome characterization of a uropathogenicFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yu-Ming CaiGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen Universitygrid.263488.3 Health Science Center, Shenzhen, China.
Kai-Wei YuSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Ji-Hong LiuSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Zhao CaiSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Zun-Hao ZhouSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
Yang LiuMedical Research Center, Southern University of Science and Technology Hospital, Shenzhen, China.
Tian-Fu WangGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen Universitygrid.263488.3 Health Science Center, Shenzhen, China.
Liang YangSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0002-2362-0128
Southern University of Science and Technology · CNShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Pseudomonas aeruginosa PAO1, 41 genes encode proteins predicted to be involved in the production or degradation of c-di-GMP, a ubiquitous secondary messenger that regulates a variety of physiological behaviors closely related to biofilm and aggregate formation. Despite extensive effort, the entire picture of this important signaling network is still unclear, with one-third of these proteins remaining uncharacterized. Here, we show that the deletion of

Indexed as

BacteriophagesEscherichia coli ProteinsBacterial ProteinsBiofilmsCyclic GMPGene Expression Regulation, BacterialPhosphoric Diester HydrolasesPhosphorus-Oxygen LyasesPseudomonas aeruginosaBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPEscherichia coli ProteinsPhosphoric Diester HydrolasesPhosphorus-Oxygen Lyasesaggregationbacteriophagecyclic-di-GMPphosphodiesterasePseudomonas aeruginosa

Identifiers

PMID35638845
PMCPMC9238385
OpenAlexW4282912778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.