Evidence map›Paper›PMID 35638834›Full record

ArticleMicrobiology spectrum2022

A Look inside the Replication Dynamics of SARS-CoV-2 in Blyth's Horseshoe Bat (

Heidi Auerswald, Dolyce H W Low, Jurre Y Siegers, Teyputita Ou, Sonita Kol, Saraden In, Martin Linster, Yvonne C F Su, Ian H Mendenhall, Veasna Duong and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Chiropteran (Animals : an open access journal from MDPI · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Heidi Auerswald *Virology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.
Dolyce H W Low *Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Jurre Y SiegersVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.
Teyputita OuVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.
Sonita KolVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.
Saraden InVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.
Martin LinsterProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0003-2636-2512
Yvonne C F SuProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Ian H MendenhallProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Veasna DuongVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.ORCID 0000-0003-0353-1678
Gavin J D SmithProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID 0000-0001-5031-468X
Erik A KarlssonVirology Unit, Institut Pasteur du Cambodgegrid.418537.c, Institut Pasteur International Network, Phnom Penh, Cambodia.ORCID 0000-0001-6004-5671
Institut Pasteur du Cambodge · KHDuke-NUS Medical School · SGDuke University · USSingHealth Duke-NUS Academic Medical Centre · SG

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00015 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HENSLEY, SCOTT · 2021 to 2025
$50.7M
Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaU01AI151758 · NIAID · INSTITUT PASTEUR · PI SAKUNTABHAI, ANAVAJ, SIMON-LORIERE, ETIENNE · 2020 to 2024
$6.7M
NIAID NIH HHS 75N93021C00015NIAID NIH HHS U01 AI151758
6 · The paper itself

Abstract

Bats are considered the natural reservoir of numerous emerging viruses such as severe acute respiratory syndrome coronaviruses (SARS-CoVs). There is a need for immortalized bat cell lines to culture and investigate the pathogenicity, replication kinetics, and evolution of emerging coronaviruses. We illustrate the susceptibility and permissiveness of a spontaneously immortalized kidney cell line (Rhileki) from Blyth's horseshoe bat (

Indexed as

ChiropteraCOVID-19AnimalsHumansKidneyPandemicsPhylogenySARS-CoV-2batbat cellscoronavirusprimary cellreservoirSARS-CoVSARS-CoV-2viral replicationvirus isolationzoonoses

Identifiers

PMID35638834
PMCPMC9241725
OpenAlexW4281751334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.