Evidence map›Paper›PMID 35638787›Full record

ArticleMicrobiology spectrum2022

Rapid Detection of Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex by High-Resolution Melting Curve Analysis.

Haoran Li, Gulibike Mulati, Yuanyuan Shang, Cong Yao, Yufeng Wang, Weicong Ren, Zhongtan Xue, Shanshan Li, Yu Pang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haoran Li *Department of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.
Gulibike Mulati *Department of Laboratory Medicine, The Eighth Affiliated Hospital of Xinjiang Medical University Urumqi, Xinjiang, People's Republic of China.
Yuanyuan Shang *Department of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.
Cong YaoDepartment of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.
Yufeng WangDepartment of Laboratory Quality Control, Innovation Alliance on Tuberculosis Diagnosis and Treatment (Beijing), Beijing, People's Republic of China.
Weicong RenDepartment of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.
Zhongtan XueDepartment of Laboratory Quality Control, Innovation Alliance on Tuberculosis Diagnosis and Treatment (Beijing), Beijing, People's Republic of China.
Shanshan LiDepartment of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.
Yu PangDepartment of Bacteriology and Immunology, Beijing Chest Hospitalgrid.414341.7, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People's Republic of China.ORCID 0000-0001-6803-9807
Capital Medical University · CNCenter for Tuberculosis Control of Guangdong Province · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of Mycobacterium abscessus complex (MABC) infection is the most noteworthy health care problem. Clarithromycin (CLA) and amikacin (AMK) constitute the cornerstone of treatment for patients infected with MABC; thus, early detection of resistance to these two drugs is essential for formulating effective therapeutic regimens. In the present study, we aimed to validate the use of MeltPro MAB assay, a melting curve analysis with dually labeled probes, on a set of clinical isolates to detect CLA and AMK resistance. A total of 103 clinical MABC strains were collected in our analysis, including 76 strains of M. abscessus

Indexed as

Mycobacterium abscessusMycobacterium Infections, NontuberculousAmikacinAnti-Bacterial AgentsClarithromycinDrug Resistance, BacterialHumansMicrobial Sensitivity TestsAmikacinAnti-Bacterial AgentsClarithromycinamikacinclarithromycinmelting curve analysisMycobacterium abscessus complexresistance

Identifiers

PMID35638787
PMCPMC9241889
OpenAlexW4281707683

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.