Evidence map›Paper›PMID 35638742›Full record

ArticlemBio2022

Modern Biophysics Redefines Our Understanding of Fungal Cell Wall Structure, Complexity, and Dynamics.

Jean-Paul Latgé, Tuo Wang

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  6. Acetylation and accessibility ofCell surface (Amsterdam, Netherlands) · 2026
    Article
  7. Article
  8. α-1,3-Glucan-Driven Remodeling of the Conidial Cell Wall in anJournal of the American Chemical Society · 2026
    Article
  9. Chaotropic Ions Reshape the Cell Wall of the Obligate HalophilebioRxiv : the preprint server for biology · 2026
    Article
  10. Review
  11. Oxidative Stress-Responsive Cell Wall Remodeling Depends on Phosphate inbioRxiv : the preprint server for biology · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. α-glucan remodeling by GH13-domain enzymes shapes fungal cell wall architecture.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jean-Paul LatgéInstitute of Molecular Biology and Biotechnology (FORTH), School of Medicine, University of Crete, Heraklion, Greece.
Tuo WangDepartment of Chemistry, Louisiana State Universitygrid.64337.35, Baton Rouge, Louisiana, USA.
Louisiana State University · USUniversity of Crete · GR

Funding

Using Solid-State NMR Spectroscopy to Elucidate Cell Wall Structural Dynamics Involved in Virulence and Drug Response of Aspergillus fumigatusR21AI149289 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI WANG, PING, WANG, TUO · 2020 to 2021
$414k
NIAID NIH HHS R21 AI149289
6 · The paper itself

Abstract

Even though the cell wall has been recognized as a crucial protective organelle for fungi, essential for its virulence and a unique emblem of this kingdom, biosynthesis of this organelle remains poorly understood. Our knowledge was based mainly in the past on the chemical analysis of cell wall mutants and on the biochemical study of a few synthases and transglycosidases. Recent developments in biophysical equipment and methods, such as solid-state nuclear magnetic resonance or cryo-electron microscopy, have promoted a better appreciation of the spatiotemporal dynamics of cell wall biosynthesis. The new information will be presented here with the cell wall of the human opportunistic pathogen Aspergillus fumigatus.

Indexed as

Aspergillus fumigatusCell WallBiophysicsCryoelectron MicroscopyFungal ProteinsHumansVirulenceFungal ProteinsAspergillus fumigatuscell wallchitinglucansglycobiologynuclear magnetic resonance

Identifiers

PMID35638742
PMCPMC9239136
OpenAlexW4281717211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.