ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2022
Abnormal intestinal milieu in posttraumatic stress disorder is not impacted by treatment that improves symptoms.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- The microbiome and PTSD: a scoping review across preclinical and clinical studies.European journal of psychotraumatology · 2026Article
- Review
- The saNeuroGut Initiative: Investigating the Gut Microbiome and Symptoms of Anxiety, Depression, and Posttraumatic Stress.Neuroimmunomodulation · 2025Article
- Gut-brain axis in post-traumatic stress disorder: microbial - mediated mechanisms and new therapeutic approaches - A narrative review.Frontiers in pharmacology · 2025Review
- The Intersection of Ultra-Processed Foods, Neuropsychiatric Disorders, and Neurolaw: Implications for Criminal Justice.NeuroSci · 2024Article
- Microglia-mediated neuroimmune suppression in PTSD is associated with anhedonia.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and Justice.International journal of environmental research and public health · 2024Article
- Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial.Frontiers in neuroscience · 2024Article
- Effects of repeated intragastric administrations with heat-inactivatedFrontiers in neuroscience · 2024Article
- A cross-sectional study of correlations among blood-based biomarkers for intestinal permeability: A pilot study of United States veterans with posttraumatic stress disorder symptoms.Brain, behavior, & immunity - health · 2023Article
- The emerging role of the gut microbiome in posttraumatic stress disorder.Brain, behavior, and immunity · 2023Review
- SubcutaneousNeurobiology of stress · 2023Article
- Post-traumatic Stress Disorder: Focus on Neuroinflammation.Molecular neurobiology · 2023Review
- Article
- Evolutionary Aspects of Diverse Microbial Exposures and Mental Health: Focus on "Old Friends" and Stress Resilience.Current topics in behavioral neurosciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Posttraumatic stress disorder (PTSD) is a psychiatric disorder, resulting from exposure to traumatic events. Current recommended first-line interventions for the treatment of PTSD include evidence-based psychotherapies, such as cognitive processing therapy (CPT). Psychotherapies are effective for reducing PTSD symptoms, but approximately two-thirds of veterans continue to meet diagnostic criteria for PTSD after treatment, suggesting there is an incomplete understanding of what factors sustain PTSD. The intestine can influence the brain and this study evaluated intestinal readouts in subjects with PTSD. Serum samples from controls without PTSD (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.