Evidence map›Paper›PMID 35638645›Full record

ArticleACS applied materials & interfaces2022

Manganese Oxide Nanozyme-Doped Diatom for Safe and Efficient Treatment of Peri-Implantitis.

Eun-Hyuk Lee, Sang-Woo Lee, Yongbeom Seo, Yu-Heng Deng, Young-Jun Lim, Ho-Beom Kwon, Kyungpyo Park, Hyunjoon Kong, Myung-Joo Kim

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

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  6. Nanotherapies Based on ROS Regulation in Oral Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Eun-Hyuk LeeDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Sang-Woo LeeDepartment of Physiology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Yongbeom SeoDepartment of Chemical and Biomolecular Engineering, Carle Illinois College of Medicine, Department of Pathobiology, Carl R. Woese Institute for Genomic Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Yu-Heng DengDepartment of Chemical and Biomolecular Engineering, Carle Illinois College of Medicine, Department of Pathobiology, Carl R. Woese Institute for Genomic Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Young-Jun LimDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Ho-Beom KwonDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Kyungpyo ParkDepartment of Physiology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.ORCID 0000-0003-4908-1270
Hyunjoon KongDepartment of Chemical and Biomolecular Engineering, Carle Illinois College of Medicine, Department of Pathobiology, Carl R. Woese Institute for Genomic Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-4680-2968
Myung-Joo KimDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.ORCID 0000-0003-2020-5284
Seoul National University · KRUniversity of Illinois Urbana-Champaign · USSeoul National University Dental Hospital · KR

Funding

Self-Locomotive Antimicrobial Micro-Robot (SLAM) Enhancing Biofilm-Infected Wound HealingR01AI160671 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2022 to 2025
$1.7M
NIAID NIH HHS R01 AI160671
6 · The paper itself

Abstract

Peri-implantitis is a major cause of dental implant failure. Bacterial biofilm contamination on the implant induces surrounding bone resorption and soft tissue inflammation, leading to severe deterioration of oral health. However, conventional biofilm removal procedures, such as mechanical decontamination and antiseptic application, are not effective enough to induce reosseointegration on decontaminated implant surfaces. This is due to (1) incomplete decontamination of the biofilm from inaccessible areas and (2) physicochemical alteration of implant surfaces caused by decontamination procedures. Herein, a safe and effective therapeutic approach for peri-implantitis is developed, which involves decontamination of implant-bound biofilms using the kinetic energy of microsized oxygen bubbles generated from the catalytic reaction between hydrogen peroxide (H

Indexed as

Anti-Infective Agents, LocalDental ImplantsDiatomsPeri-ImplantitisHumansHydrogen PeroxideManganese CompoundsOxidesAnti-Infective Agents, LocalDental ImplantsHydrogen PeroxideManganese Compoundsmanganese oxideOxidesbiofilmdiatomimplant decontaminationmanganese oxidenanozymeperi-implantitisreosseointegration

Identifiers

PMID35638645
PMCPMC11445715
OpenAlexW4282931369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.