Evidence map›Paper›PMID 35638550›Full record

ArticleHaematologica2022

Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring

Agatheeswaran Subramaniam, Carl Sandén, Larissa Moura-Castro, Kristijonas Žemaitis, Ludwig Schmiderer, Aurelie Baudet, Alexandra Bäckström, Elin Arvidsson, Simon Hultmark, Natsumi Miharada and 4 more

Abstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Agatheeswaran SubramaniamMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund. agatheeswaran.subramaniam@med.lu.se.
Carl SandénDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund.
Larissa Moura-CastroDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund.
Kristijonas ŽemaitisMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Ludwig SchmidererMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Aurelie BaudetMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Alexandra BäckströmMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Elin ArvidssonMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Simon HultmarkMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Natsumi MiharadaMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Mattias MagnussonMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund.
Kajsa PaulssonDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund.
Thoas FioretosDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund.
Jonas LarssonMolecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund. jonas.larsson@med.lu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Myeloid, AcuteSynthetic Lethal MutationsCell Cycle ProteinsCohesinsHumansMutationCell Cycle ProteinsCohesinsSTAG2 protein, human

Identifiers

PMID35638550
PMCPMC9425301

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.