ArticleAddiction (Abingdon, England)2022
Association of opioid use disorder with healthcare utilization and cost in a public health system.
Article in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- The positivity rate of opioid drug urine testing in an emergency department between 2016 and 2024, before and after the introduction of fentanyl testing.Substance abuse treatment, prevention, and policy · 2026Article
- Reducing opioid prescriptions does not increase rate of refills or new opioid requests: evidence from a randomized trial.Health affairs scholar · 2026Article
- Long-Term Exercise Interventions for Reducing Drug Craving in People with Drug Use Disorder: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2025Review
- Fentanyl Initiation Rate Following the Requirement for Specialist Approval.Journal of general internal medicine · 2025Observational
- Treatment of sleep-disordered breathing in opioid users with adaptive servo-ventilation: a subgroup analysis of the European READ-ASV registry.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Type 1 Diabetes/Hidradenitis Suppurativa Comorbidity-A Population-Based Study.Journal of clinical medicine · 2025Article
- Association Between Opioid Use and Emergency Department Visits for Spine-Related Disorders.Journal of pain research · 2025Article
- Observational
- Complication Rates After Ultrasonography-Guided Nerve Blocks Performed in the Emergency Department.JAMA network open · 2024Observational
- Prescription opioid use in Israel - the tide has risen, but it's not a tidal wave.Israel journal of health policy research · 2024Article
- Overlooking the obvious: the importance of communicating safety and risks of opioids-the Israeli context.Frontiers in pharmacology · 2024Article
- Does Opioid Use Disorder Matter for Health Care Utilization Among Lung Cancer Patients? Evidence from U.S. Hospitals During 2016-2020.Clinical drug investigation · 2023Article
- Trends and correlated outcomes in population-level prescription opioid and transdermal fentanyl use in Israel.Israel journal of health policy research · 2023Article
- Association of opioid use disorder with healthcare utilization and cost in a public health system.Addiction (Abingdon, England) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo quantify the healthcare costs associated with opioid use disorder among members in a public healthcare system and compare them with healthcare costs in the general population.
designRetrospective cohort study.
settingInpatient and outpatient care settings of Israel's largest public healthcare provider (that covers 4.7 million members).
participantsParticipants included 1173 members who had a diagnosis of opioid use disorder in the years between 2013 and 2018. Each patient was matched with 10 controls based on age and sex. MEASUREMENTS: The main outcome was monthly healthcare costs.
findingsThe mean monthly healthcare cost of members with opioid use disorder was $1102 compared with $211 among controls (5.2-fold difference; 95% CI, 4.6-6.0). After excluding members with heroin related diagnoses before the index date (to focus on prescription opioids), this healthcare cost ratio did not substantially change (4.6-fold; 95% CI, 3.9-5.4). Members with opioid use disorder under the age of 65 years had a cost difference of 6.1-fold (95% CI, 5.2-7.1), whereas those 65 years and older experienced cost difference of 3.4-fold (95% CI, 2.6-4.5), compared with controls. The category with the highest cost for members with opioid use disorder was inpatient services, which was 8.7-fold (95%CI, 7.2-10.4) greater than among controls.
conclusionsHealthcare costs among individuals with opioid use disorder in Israel's public health system are substantially higher than among controls, at least partially attributable to prescription opioid use disorder. Differences are greater among individuals under 65 years.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.