Evidence map›Paper›PMID 35638355›Full record

ArticleJournal of diabetes investigation2022

Perioperative C-peptide index is associated with the status of diabetes management after pancreatectomy.

Masataka Shikata, Daisuke Chujo, Asako Enkaku, Akiko Takikawa-Nishida, Hisae Honoki, Shinnosuke Yamada-Matsukoshi, Maki Nakagawa-Yokoyama, Miki Kamigishi, Shinya Inagawa, Shiho Fujisaka and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Masataka ShikataFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.ORCID https://orcid.org/0000-0001-9314-6313
Daisuke ChujoFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Asako EnkakuFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Akiko Takikawa-NishidaFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Hisae HonokiFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Shinnosuke Yamada-MatsukoshiFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Maki Nakagawa-YokoyamaFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Miki KamigishiFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Shinya InagawaFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Shiho FujisakaFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.
Kunimasa YagiFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.ORCID https://orcid.org/0000-0002-6805-6428
Kazuto ShibuyaDepartment of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Tsutomu FujiiDepartment of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Kazuyuki TobeFirst Department of Internal Medicine, University of Toyama, Toyama, Japan.ORCID https://orcid.org/0000-0003-0015-0255
University of Toyama · JPToyama University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThis study aimed to identify the clinical factors affecting postoperative residual pancreatic β-cell function, as assessed by the C-peptide index (CPI), and to investigate the association between perioperative CPI and the status of diabetes management after pancreatectomy. MATERIALS AND

methodsThe associations between perioperative CPI and clinical background, including surgical procedures of pancreatectomy, were analyzed in 47 patients who underwent pancreatectomy, and were assessed for pre-and postoperative CPI. The association between perioperative CPI and glycemic control after pancreatectomy was investigated.

resultsThe low postoperative CPI group (CPI <0.7) had longer duration of diabetes (17.5 ± 14.5 vs 5.5 ± 11.0 years, P = 0.004), a higher percentage of sulfonylurea users (41.7 vs 8.7%, P = 0.003) and a greater number of drug categories used for diabetes treatment (1.9 ± 1.1 vs 0.8 ± 0.8, P <0.001) than did the high postoperative CPI group. Postoperative CPI was higher (1.4 ± 1.2 vs 0.7 ± 0.6, P = 0.039) in patients with low glycosylated hemoglobin (<7.0%) at 6 months after pancreatectomy; preoperative (2.0 ± 1.5 vs 0.7 ± 0.5, P = 0.012) and postoperative CPI (2.5 ± 1.4 vs 1.4 ± 1.1, P = 0.020) were higher in non-insulin users than in insulin users at 6 months after surgery.

conclusionsThe duration of diabetes and preoperative diabetes treatment were associated with residual pancreatic β-cell function after pancreatectomy. Furthermore, perioperative β-cell function as assessed by CPI was associated with diabetes management status after pancreatectomy.

Indexed as

Diabetes MellitusPancreatectomyC-PeptideGlycated HemoglobinHumansPostoperative ComplicationsRetrospective StudiesC-PeptideGlycated HemoglobinC-peptideInsulin secretionPancreatectomy

Identifiers

PMID35638355
PMCPMC9533048
OpenAlexW4281887506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.