ArticleCurrent rheumatology reviews2025
Neuropathic Pain in Patients with Knee Osteoarthritis: Relation with Comorbidities and Functional Status.
Article in Current rheumatology reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 citations in OpenAlex.
- Frequency and factors associated with neuropathic pain in patients with knee osteoarthritis.Osteoarthritis and cartilage open · 2026Article
- Understanding Pain in Osteoarthritis: A Clinical Framework Based on the Biopsychosocial Model.Topics in geriatric rehabilitation · 2026Article
- Magnetoencephalographic Spectral Abnormalities and Explainable Machine Learning of Neuropathic-Like Pain in Knee Osteoarthritis.Journal of pain research · 2026Article
- Neuropathic Pain Associated With First Metatarsophalangeal Joint Osteoarthritis: Frequency and Associated Factors.Arthritis care & research · 2023Article
- Eumycotic mycetoma involving the right foot: A new Tunisian case.Clinical case reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to evaluate the prevalence of neuropathic pain components in knee osteoarthritis (OA) patients and to identify the relation between associated neuropathic pain and comorbidities, pain intensity, function, and radiographic severity of knee OA.
methodsThis cross-sectional study enrolled patients with knee OA (ACR criteria 1986). Visual Analog Scale (VAS) and DN4 questionnaires were performed for each patient. A score of DN4≥4/10 was classified as diagnostic for neuropathic pain. Functional impairment was estimated using the short form of the Knee injury and Osteoarthritis Outcome Score (KOOS-PS) and radiographs were rated using the Kellgren Lawrence (KL).
resultsWe recruited 101 patients with a sex ratio was 0.1. The mean age was 65.5 ± 10.8 years. The mean duration of symptoms was 3.5 years. At least one comorbidity was revealed for 88.1% of patients. Mean VAS pain was 6.5 ± 1.69. The mean DN4 score was 4.8 ± 2.4. The prevalence of NP (DN4≥4) was detected at 68.3%. The most frequently described NP characteristic was the sensation of burning (74%). The mean KOOS-PS score was 46.4 ± 19.2. Based on KL grading, 78.2% of OA were classified as grade III-IV. Female gender, number of comorbidities, bilateral knee OA, mean VAS pain, and mean KOOS-PS score were significantly higher in the neuropathic pain group when compared to the group without neuropathic (respectively: p = 0.01, p = 0.04, p = 0.017, p = 0.00, p = 0.00). In multivariate regression, KOOS-PS and bilateral knee OA were independently associated with NP.
conclusionOur results highlight the frequent NP in patients with knee OA (68.3%) and its relation with function and comorbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.