ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2023
Association of intraplacental oxygenation patterns on dual-contrast MRI with placental abnormality and fetal brain oxygenation.
Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Recent innovations in placental MRI: Integrating visualization and functional imaging.Placenta · 2026Review
- [Association Study of Parity With Adverse Pregnancy Outcomes].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Placental contractions in uncomplicated pregnancies.PloS one · 2026Observational
- Leveraging Machine Learning to Predict and Assess Disparities in Severe Maternal Morbidity in Maryland.Healthcare (Basel, Switzerland) · 2025Article
- Role of damage-associated molecular patterns in the pathogenesis and therapeutics of traumatic brain injury.Burns & trauma · 2025Review
- Quantitative and longitudinal assessment of human placental inflammation using diffusion basis spectrum imaging.npj women's health · 2025Article
- Advanced magnetic resonance imaging detects altered placental development in pregnancies affected by congenital heart disease.Scientific reports · 2024Article
- Advanced magnetic resonance imaging detects altered placental development in pregnancies affected by congenital heart disease.Research square · 2024Article
- 3D bi-directional transformer U-Net for medical image segmentation.Frontiers in big data · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesMost human in-vivo placental imaging techniques are unable to distinguish and characterize various placental compartments, such as the intervillous space (IVS), placental vessels (PV) and placental tissue (PT), limiting their specificity. We describe a method that employs T2* and diffusion-weighted magnetic resonance imaging (MRI) data to differentiate automatically placental compartments, quantify their oxygenation properties and identify placental lesions (PL) in vivo. We also investigate the association between placental oxygenation patterns and fetal brain oxygenation.
methodsThis was a prospective study conducted between 2018 and 2021 in which dual-contrast clinical MRI data (T2* and diffusion-weighted MRI) were acquired from patients between 20 and 38 weeks' gestation. We trained a fuzzy clustering method to analyze T2* and diffusion-weighted MRI data and assign placental voxels to one of four clusters, based on their distinct imaging domain features. The new method divided automatically the placenta into IVS, PV, PT and PL compartments and characterized their oxygenation changes throughout pregnancy.
resultsA total of 27 patients were recruited, of whom five developed pregnancy complications. Total placental oxygenation level and T2* did not demonstrate a statistically significant temporal correlation with gestational age (GA) (R
conclusionBased on clinically feasible dual-MRI, our method enables accurate spatiotemporal quantification of placental compartment and fetal brain oxygenation across different GAs. This information should improve our knowledge of human placenta development and its relationship with normal and abnormal pregnancy. © 2022 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
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